ArticleOrganic letters2011
Environment- and sequence-dependence of helical type in membrane-spanning peptides composed of β3-amino acids.
Article in Organic letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Catalytic peptide assemblies.Chemical Society reviews · 2018Review
- Functional characterization of a melittin analog containing a non-natural tryptophan analog.Biopolymers · 2015Article
- α-Helix mimicry with α/β-peptides.Methods in enzymology · 2013Article
- Computational design of a β-peptide that targets transmembrane helices.Journal of the American Chemical Society · 2011Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
Abstract
Transmembrane (TM) β-peptides comprised of acyclic β(3)-amino acids demonstrate equilibrium between 12- and 14-helical structures in an environment- and sequence-dependent manner. Circular dichroism (CD) spectra of TM β(3)-peptides may be described as linear combinations of the 12- and 14-helical CD spectra. The apparent malleability of β(3)-substituted acyclic β-peptides has practical implications for foldamer design, as it suggests that both the 14-helix and 12-helix might be reasonable platforms for molecular recognition.
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Registered trials
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