Evidence map›Paper›PMID 21650153›Full record

ArticleJournal of natural products2011

Biosynthetic origin of the 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid moiety and absolute configuration of pahayokolides A and B.

Li Liu, Daniel W Bearden, Kathleen S Rein

Abstract read
In one paragraph

Article in Journal of natural products, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. The Desotamide Family of Antibiotics.Antibiotics (Basel, Switzerland) · 2020
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Li LiuDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, USA.
Daniel W Bearden
Kathleen S Rein

Funding

Pilot--Molecular Monitoring of Toxic DinoflagellatesS11ES011181 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI REIN, KATHLEEN S · 2001 to 2011
$6.9M
NIEHS NIH HHS S11 ES011181NIEHS NIH HHS S11 ES11181
6 · The paper itself

Abstract

Pahayokolides A and B are cyclic undecapeptides that were isolated from the cyanobacterium Lyngbya sp. They contain the unusual α-hydroxy-β-amino acid 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid (Athmu). The absolute configurations of the amino acids of the pahayokolides, except for the four oxygen-bearing stereocenters of Athmu, have been determined by Marphy's method. Incorporation of labeled leucine and acetate precursors into the pahayokolides has established that Athmu is derived from a leucine or α-keto isocaproic acid starter unit, which is further extended with three acetate units.

Indexed as

CyanobacteriaFatty AcidsLyngbya ToxinsMolecular StructurePeptides, Cyclic3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acidFatty AcidsLyngbya Toxinspahayokolide Apahayokolide BPeptides, Cyclic

Identifiers

PMID21650153
PMCPMC3163906

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.