ArticleVirology journal2011
Prevalence of hepatitis B virus genotypes in HBsAg positive individuals of Afghanistan.
Article in Virology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- A Recent Prevalence of Hepatitis B Virus (HBV) Genotypes and Subtypes in Asia: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- COVID-19 and the Taliban-shadowed intensification of the neglected fate of viral hepatitis in Afghanistan.Annals of medicine and surgery (2012) · 2022Article
- Health Status of Afghan Refugees in Europe: Policy and Practice Implications for an Optimised Healthcare.International journal of environmental research and public health · 2022Review
- Prevalence and geo-clinicodemographic factors associated with hepatitis B vaccination among healthcare workers in five developing countries.BMC infectious diseases · 2022Article
- Molecular epidemiology of Hepatitis B virus, Hepatitis C virus, and Hepatitis D virus in general population of Afghanistan.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Hepatitis B virus genotypes: epidemiological and clinical relevance in Asia.Hepatology international · 2016Review
- Genotyping and Mutation Pattern in the Overlapping MHR Region of HBV Isolates in Southern Khorasan, Eastern Iran.Hepatitis monthly · 2016Article
- Burden of Gastrointestinal and Liver Diseases in Middle East and North Africa: Results of Global Burden of Diseases Study from 1990 to 2010.Middle East journal of digestive diseases · 2015Review
- Distribution of hepatitis B virus genotypes in azerbaijani patients with chronic hepatitis B infection.Hepatitis monthly · 2014Article
- Hepatitis B Virus Genotypes Distribution with HBsAg Positive in the North of Iran (Mazandaran) During 2011-2014.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2014Article
- Prevalence and genotypes of hepatitis B virus infection in patients underwent coronary angiography and coronary artery bypass grafting in mazandaran heart center, sari, iran.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2014Article
- Hepatitis B genotypes in iran.Materia socio-medica · 2014Article
- Naturally occurring core immune-escape and carboxy-terminal mutations\truncations in patients with e antigen negative chronic hepatitis B.Hepatology international · 2012Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe structural and functional differences between hepatitis B virus (HBV) genotypes are the mainstay to severity, complications, treatment and possibly vaccination against the virus. This study was conducted to determine the HBV genotypes in HBsAg positive patients of Afghanistan as no such large scale data available previously.
methodsTwo hundred and fourteen HBsAg-positive patients were included in this study. All patients were anti-HCV and anti-HIV negative. All the samples were confirmed for HBV DNA with nested PCR while HBV DNA positive samples were subjected to type specific PCR for HBV genotyping (A-F).
resultsOf the total samples, 168 (78.5%) were males and 46 (21.49%) females, aged ranged between 18 to 71 years. This study demonstrated that genotype D (35.67%) is the predominant genotype circulating in Afghani's population. Genotype C was observed in 32.16% followed by genotype A (19.30%), and genotype B (7.02%) while 6.07% of the individuals were not typed.
conclusionThis study has shown a heterogeneous distribution of HBV genotypes. Further more, extensive studies are required to investigate genetic and geographical divergence and characteristics of the virus in the country, as no such large sample sized study has been carried out so far in this country.
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