SynthesisIntensive care medicine2011
Prognostic models for predicting mortality in elderly ICU patients: a systematic review.
Synthesis in Intensive care medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.The Cochrane database of systematic reviews · 2026Pooled it
- Prediction of Morbidity and Mortality After Esophagectomy: A Systematic Review.Annals of surgical oncology · 2024Pooled it
- Measurement properties of comorbidity indices in maternal health research: a systematic review.BMC pregnancy and childbirth · 2017Pooled it
- Individual risk modelling for esophagectomy: a systematic review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2014Pooled it
- Evaluation of SOFA-2 Score Performance Across Demographic Subgroups: An External Validation Study Using MIMIC-IV.medRxiv : the preprint server for health sciences · 2026Article
- Parsimonious Logistic Regression Models for 90-Day Mortality Prediction in the Intensive Care Unit.Cureus · 2025Article
- Upper gastrointestinal bleeding differences between older and younger adults: should bleeding in non-cirrhotic patients be considered a geriatric syndrome?Therapeutic advances in gastroenterology · 2025Article
- Continuous monitoring of physiological data using the patient vital status fusion score in septic critical care patients.Scientific reports · 2024Article
- Combined and intraoperative risk modelling for oesophagectomy: A systematic review.World journal of gastrointestinal surgery · 2023Article
- Clinically Interpretable Machine Learning Models for Early Prediction of Mortality in Older Patients with Multiple Organ Dysfunction Syndrome: An International Multicenter Retrospective Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Preoperative risk modelling for oesophagectomy: A systematic review.World journal of gastrointestinal surgery · 2023Article
- Elderly in the ICU.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- Elderly Patients and Management in Intensive Care Units (ICU): Clinical Challenges.Clinical interventions in aging · 2023Review
- The Clinical Application of Machine Learning-Based Models for Early Prediction of Hemorrhage in Trauma Intensive Care Units.Journal of personalized medicine · 2022Article
- Age as Maestro or Solo Instrument in Opera of Death.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Age, Frailty, Resuscitation and Intensive Care: With Reference to COVID-19.Geriatrics (Basel, Switzerland) · 2021Article
- Age is not a risk factor in survival of severely ill patients with co-morbidities in a medical intensive care unit.Irish journal of medical science · 2021Article
- Utility of SpO2/FiO2 ratio for acute hypoxemic respiratory failure with bilateral opacities in the ICU.PloS one · 2021Article
- Article
- Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo systematically review prognostic research literature on development and/or validation of mortality predictive models in elderly patients.
methodsWe searched the Scopus database until June 2010 for articles aimed at validating prognostic models for survival or mortality in elderly intensive care unit (ICU) patients. We assessed the models' fitness for their intended purpose on the basis of barriers for use reported in the literature, using the following categories: (1) clinical credibility, (2) methodological quality (based on an existing quality assessment framework), (3) external validity, (4) model performance, and (5) clinical effectiveness.
resultsSeven studies were identified which met our inclusion criteria, one of which was an external validation study. In total, 17 models were found of which six were developed for the general adult ICU population and eleven specifically for elderly patients. Cohorts ranged from 148 to 12,993 patients and only smaller ones were obtained prospectively. The area under the receiver operating characteristic curve (AUC) was most commonly used to measure performance (range 0.71-0.88). The median number of criteria met for clinical credibility was 4.5 out of 7 (range 2.5-5.5) and 17 out of 20 for methodological quality (range 15-20).
conclusionsAlthough the models scored relatively well on methodological quality, none of them can be currently considered sufficiently credible or valid to be applicable in clinical practice for elderly patients. Future research should focus on external validation, addressing performance measures relevant for their intended use, and on clinical credibility including the incorporation of factors specific for the elderly population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.