ArticleInternational journal of medical sciences2011
The impact of a nationwide antibiotic restriction program on antibiotic usage and resistance against nosocomial pathogens in Turkey.
Article in International journal of medical sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of national interventions to promote responsible antibiotic use: a systematic review.The Journal of antimicrobial chemotherapy · 2020Pooled it
- Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map.PLoS medicine · 2019Pooled it
- Administrative interventions in antimicrobial stewardship: a global scoping review of all WHO regions.Frontiers in pharmacology · 2026Review
- Economic costing methodologies for drug-resistant bacterial infections in humans in low-and middle-income countries: a systematic review.Health economics review · 2025Review
- Impact of cascade reporting of antimicrobial susceptibility on fluoroquinolone and meropenem consumption at a Veterans' Affairs medical center.Infection control and hospital epidemiology · 2022Article
- New insights and antimicrobial stewardship opportunities in viral pneumonia: five lung ultrasound cases.Wiener klinische Wochenschrift · 2021Article
- The Effect of Antibiotic Restriction Programs on Prevalence of Antimicrobial Resistance: A Systematic Review and Meta-Analysis.Open forum infectious diseases · 2021Article
- Implementation of Antibiotic Stewardship in a University Hospital Setting.Antibiotics (Basel, Switzerland) · 2021Article
- Inapropriate use of antibiotics effective against gram positive microorganisms despite restrictive antibiotic policies in ICUs: a prospective observational study.BMC infectious diseases · 2020Observational
- Reducing the Consumption of Antibiotics: Would That Be Enough to Slow Down the Dissemination of Resistances in the Downstream Environment?Frontiers in microbiology · 2020Article
- Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases.Infection · 2016Article
- A Review of Quality Measures for Assessing the Impact of Antimicrobial Stewardship Programs in Hospitals.Antibiotics (Basel, Switzerland) · 2016Review
- Wide distribution of carbapenem resistant Acinetobacter baumannii in burns patients in Iran.Frontiers in microbiology · 2015Article
- Carbapenem Restriction and its Effect on Bacterial Resistance in an Intensive Care unit of a Teaching Hospital.Iranian journal of pharmaceutical research : IJPR · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAntimicrobial resistance among microorganisms is a global concern. In 2003, a nationwide antibiotic restriction program (NARP) was released in Turkey. In this study we evaluated the effect of NARP on antibiotic consumption, antimicrobial resistance, and cost. MATERIALS AND
methodsThe data obtained from all of the four university hospitals, and one referral tertiary-care educational state hospital in Ankara. Antimicrobial resistance profiles of 14,233 selected microorganisms all grown in blood cultures and antibiotic consumption from 2001 to 2005 were analyzed retrospectively.
resultsA negative correlation was observed between the ceftriaxone consumption and the prevalence of ceftriaxone resistant E.coli and Klebsiella spp. (rho:-0.395, p:0.332 and rho:-0.627, p:0.037, respectively). The decreased usage of carbapenems was correlated with decreased carbapenems-resistant Pseudomonas spp. and Acinetobacter spp (rho:0.155, p:0.712 and rho:0.180, p:0.668, respectively for imipenem). Methicillin resistance rates of S.aureus were decreased from 44% to 41%. After two years of NARP 5,389,155.82 USD saving occurred.
conclusionNARP is effective in lowering the costs and antibiotic resistance.
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