ArticlePediatric reports2011
Laboratory aid to the diagnosis and therapy of infection in the neonate.
Article in Pediatric reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05985174 (Role of Neutrophil CD64 and Monocyte HLA-DR Markers in the Dignosis of Neonatal Sepsis), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of Neutrophil CD64 and Monocyte HLA-DR Markers in the Dignosis of Neonatal Sepsis
Who cites it
17 citing papers in PubMed, 8 citations in OpenAlex.
- Unveiling the Power of Platelet-to-Lymphocyte Ratio as a Game-Changer in Late-Onset Neonatal Sepsis Diagnosis.Children (Basel, Switzerland) · 2025Article
- A decade of neonatal sepsis in Stockholm, Sweden: Gram-positive pathogens were four times as common as Gram-negatives.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- Salivary C-reactive protein and mean platelet volume as possible diagnostic markers for late-onset neonatal pneumonia.World journal of clinical pediatrics · 2024Article
- Soluble TREM-1 is not a useful biomarker in the diagnosis of early-onset neonatal sepsis.Future microbiology · 2024Article
- Tackling Neonatal Sepsis-Can It Be Predicted?International journal of environmental research and public health · 2023Article
- 2.5 Million Annual Deaths-Are Neonates in Low- and Middle-Income Countries Too Small to Be Seen? A Bottom-Up Overview on Neonatal Morbi-Mortality.Tropical medicine and infectious disease · 2022Review
- Monocyte-to-HDL ratio and non-HDL cholesterol were predictors of septic shock in newborns.Clinics (Sao Paulo, Brazil) · 2022Article
- Variations in Antibiotic Use and Sepsis Management in Neonatal Intensive Care Units: A European Survey.Antibiotics (Basel, Switzerland) · 2021Article
- The Association of Laboratory Test Abnormalities With Mortality Risk in Pediatric Intensive Care.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2021Article
- A study of red cell distribution width and neonatal sepsis at Soba University Hospital, Khartoum, Sudan.Sudanese journal of paediatrics · 2021Article
- Sepsis calculator implementation reduces empiric antibiotics for suspected early-onset sepsis.European journal of pediatrics · 2018Article
- Precision Medicine for Neonatal Sepsis.Frontiers in molecular biosciences · 2018Review
- Use of early biomarkers in neonatal brain damage and sepsis: state of the art and future perspectives.BioMed research international · 2015Review
- Study on the usefulness of APR scores from the viewpoint of proinflammatory cytokines.Disease markers · 2015Article
- The Sex Differences of Morphology and Immunology of SIRS of Newborn Wistar Rats.International scholarly research notices · 2014Article
- Diagnostic utility of neutrophil CD64 as a marker for early-onset sepsis in preterm neonates.PloS one · 2014Article
- LPS induces cardiomyocyte injury through calcium-sensing receptor.Molecular and cellular biochemistry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the advances in perinatal and neonatal care and use of newer potent antibiotics, the incidence of neonatal sepsis remains high and the outcome is still severe. For years, investigators have sought a test or panel of tests able to identify septic neonates accurately and rapidly in order to obtain an early diagnosis and develop a specific effective treatment for a successful outcome. In addition to the standard procedures (blood, CSF, and urine cultures), such panels have included a combination of haematological investigations (total, differential and immature cell counts), and levels of acute-phase reactants (principally CRP and procalcitonin), and cytokines (such as IL-6 or neutrophil CD64). Furthermore, the science of proteomics and genomics has been applied to the search for bio-markers, production of protein profiles and genetic polymorphisms that can rapidly help the prediction, early diagnosis, and treatment of human diseases, but, for now, data are as yet insufficient to confirm their validity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.