ReviewCurrent opinion in HIV and AIDS2011
HIV-1 treatment as prevention: the good, the bad, and the challenges.
Review in Current opinion in HIV and AIDS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Promoting HIV care continuum outcomes among people who use drugs and alcohol: a systematic review of randomized trials evaluating behavioral HIV care interventions published from 2011 to 2023.BMC public health · 2023Pooled it
- HIV care and treatment experiences among female sex workers living with HIV in sub-Saharan Africa: A systematic review.African journal of AIDS research : AJAR · 2016Pooled it
- Clinical uncertainties, health service challenges, and ethical complexities of HIV "test-and-treat": a systematic review.American journal of public health · 2013Pooled it
- Willingness to use HIV prevention methods among vaccine efficacy trial participants in Soweto, South Africa: discretion is important.BMC public health · 2020Trial
- Alcohol and drug use outcomes among vulnerable women living with HIV: results from the Western Cape Women's Health CoOp.AIDS care · 2014Trial
- Can combination prevention strategies reduce HIV transmission in generalized epidemic settings in Africa? The HPTN 071 (PopART) study plan in South Africa and Zambia.Journal of acquired immune deficiency syndromes (1999) · 2013Trial
- Prevention of HIV-1 infection with early antiretroviral therapy.The New England journal of medicine · 2011Trial
- Care during ART scale-up: surviving the HIV epidemic in Ethiopia.BioSocieties · 2022Article
- Poor quality of life and incomplete self-reported adherence predict second-line ART virological failure in resource-limited settings.AIDS care · 2021Article
- Substance Use Predicts Sustained Viral Suppression in a Community Cohort of Sexual and Gender Minority Youth Living with HIV.AIDS and behavior · 2021Article
- Cryptococcus neoformans infection in Human Immunodeficiency Virus (HIV)-infected and HIV-uninfected patients at an inner-city tertiary care hospital in the Bronx.Medical mycology · 2020Article
- Growing Acceptability of Undetectable = Untransmittable but Widespread Misunderstanding of Transmission Risk: Findings From a Very Large Sample of Sexual Minority Men in the United States.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Weighing the Evidence of Efficacy of Oral PrEP for HIV Prevention in Women in Southern Africa.AIDS research and human retroviruses · 2018Review
- Psychosocial Functioning and Decisional Balance to Use Condoms in a Racially/Ethnically Diverse Sample of Young Gay/Bisexual Men Who Have Sex with Men.Archives of sexual behavior · 2018Article
- Adherence to antiretroviral therapy among HIV/ AIDS patients in the context of early treatment initiation in Vietnam.Patient preference and adherence · 2018Article
- Article
- Factors associated with perceived accuracy of the Undetectable = Untransmittable slogan among men who have sex with men: Implications for messaging scale-up and implementation.Journal of the International AIDS Society · 2018Article
- Measures of human immunodeficiency virus (HIV) community viral load and HIV incidence among people who inject drugs.Annals of epidemiology · 2018Article
- Hypo-osmolar Formulation of Tenofovir (TFV) Enema Promotes Uptake and Metabolism of TFV in Tissues, Leading to Prevention of SHIV/SIV Infection.Antimicrobial agents and chemotherapy · 2018Article
- Epidemiological impact of achieving UNAIDS 90-90-90 targets for HIV care in India: a modelling study.BMJ open · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThis work focuses on the use of antiretroviral agents to prevent the sexual transmission of HIV-1. RECENT
findingsTwo randomized clinical trials demonstrated that antiretroviral agents provided before exposure to HIV-1 offer substantial protection, ostensibly directly proportional to the concentration of antiretroviral therapy (ART) in the genital secretions. Intense focus on the use of HIV treatment as prevention has led to publication of modeling exercises, ecological studies, and observational studies, most of which support the potential benefits of ART. However, the logistical requirements for successful use of ART for prevention are considerable. SUMMARY: ART will serve as a cornerstone of combination prevention of HIV-1. Continued research will be essential to measure anticipated benefits and to detect implementation barriers and untoward consequences of such a program, especially increases in primary ART resistance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.