ArticleGut microbes
The remarkable capacity for gut microbial and host interactions.
Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Epigenetic phase variation in the gut microbiome enhances bacterial adaptation.Cell host & microbe · 2026Article
- Effect ofFrontiers in nutrition · 2021Article
- Analysis of the Gut Microbiome of Wild and Captive Père David's Deer.Frontiers in microbiology · 2019Article
- Early microbial colonization affects DNA methylation of genes related to intestinal immunity and metabolism in preterm pigs.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- The environment, epigenome, and asthma.The Journal of allergy and clinical immunology · 2017Review
- Epigenome-Microbiome crosstalk: A potential new paradigm influencing neonatal susceptibility to disease.Epigenetics · 2016Article
- Article
- Impact of chronic exposure to low doses of chlorpyrifos on the intestinal microbiota in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) and in the rat.Environmental science and pollution research international · 2013Article
- Monotonous diets protect against acute colitis in mice: epidemiologic and therapeutic implications.Journal of pediatric gastroenterology and nutrition · 2013Article
- Article
- Article
- Epigenetics and the developmental origins of inflammatory bowel diseases.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2012Review
- Microbiota separation and C-reactive protein elevation in treatment-naïve pediatric granulomatous Crohn disease.Journal of pediatric gastroenterology and nutrition · 2012Article
- SMAD4 haploinsufficiency associates with augmented colonic inflammation in select humans and mice.Annals of clinical and laboratory science · 2012Article
- Maternal micronutrients can modify colonic mucosal microbiota maturation in murine offspring.Gut microbesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The stunning complexity of the resident microbiota and the intricate pathways of microbial and host interactions provide a massive adaptive capacity for mammals. In this addendum we reflect on our recent publication on Toll-like receptor 2 deficiency related colonic mucosal epigenetic, immunologic and microbiomic changes. Our findings underscored the tremendous flexibility of the gut and its microbiota. This flexibility can provide means to overcome significant environmental or genetic challenges. In the meantime, the challenged intestinal system may become vulnerable to otherwise tolerable insults. In such instances, the fine-tuned mutualistic balance between the gut and its microflora may collapse leading to dysbiosis and disease. The ultimate challenge for biomedical research in these cases is to find optimal means for the restoration and maintenance of healthy host physiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.