Evidence map›Paper›PMID 21646431›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2011

Nucleosome positioning in Saccharomyces cerevisiae.

An Jansen, Kevin J Verstrepen

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 128 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Regulation of Catalase Expression and Activity byJournal of fungi (Basel, Switzerland) · 2024
    Article
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  16. Identification of clade-wide putativeHorticulture research · 2023
    Article
  17. Article
  18. Control of Gene Expression via the Yeast CWI Pathway.International journal of molecular sciences · 2022
    Review
  19. regCNN: identifyingComputational and structural biotechnology journal · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

An JansenVIB Laboratory for Systems Biology, Bio-Incubator, Gaston Geenslaan 1, B-3001 Leuven, Belgium.
Kevin J Verstrepen
KU Leuven · BE

Funding

European Research Council 241426
6 · The paper itself

Abstract

The DNA of eukaryotic cells is spooled around large histone protein complexes, forming nucleosomes that make up the basis for a high-order packaging structure called chromatin. Compared to naked DNA, nucleosomal DNA is less accessible to regulatory proteins and regulatory processes. The exact positions of nucleosomes therefore influence several cellular processes, including gene expression, chromosome segregation, recombination, replication, and DNA repair. Here, we review recent technological advances enabling the genome-wide mapping of nucleosome positions in the model eukaryote Saccharomyces cerevisiae. We discuss the various parameters that determine nucleosome positioning in vivo, including cis factors like AT content, variable tandem repeats, and poly(dA:dT) tracts that function as chromatin barriers and trans factors such as chromatin remodeling complexes, transcription factors, histone-modifying enzymes, and RNA polymerases. In the last section, we review the biological role of chromatin in gene transcription, the evolution of gene regulation, and epigenetic phenomena.

Indexed as

Genome, FungalAnimalsBiological EvolutionChromosome MappingEukaryotaGene Expression Regulation, FungalNucleosomesSaccharomyces cerevisiaeYeastsNucleosomes

Identifiers

PMID21646431
PMCPMC3122627
OpenAlexW2123799610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.