Evidence map›Paper›PMID 21646378›Full record

ReviewCold Spring Harbor perspectives in biology2011

Lipid polymorphisms and membrane shape.

Vadim A Frolov, Anna V Shnyrova, Joshua Zimmerberg

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

  1. Article
  2. Devising a divisome for synthetic cells.Nature reviews. Chemistry · 2026
    Review
  3. Response of Psychrotolerant FungusInternational journal of molecular sciences · 2026
    Article
  4. Cylindrical Crystallization of CaInternational journal of molecular sciences · 2026
    Review
  5. Article
  6. Article
  7. Cold adaptation mechanisms of the psychrotolerant filamentous ascomycete Psychrophilomyces antarcticus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  8. Article
  9. On an RNA-Membrane Protogenome.Life (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Sorting of complex sphingolipids within the cellular endomembrane systems.Frontiers in cell and developmental biology · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vadim A FrolovUnidad de Biofisica (Centro Mixto CSIC-UPV/EHU), Leioa 48940, Spain.
Anna V Shnyrova
Joshua Zimmerberg

Funding

Membrane Remodeling in Viral Infection, Parasite Replication, and Traumatic Brain InjuryZIAHD001409 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ZIMMERBERG, JOSHUA · 2009 to 2025
$29.9M
Mechanisms and Intracellular Components in Exocytosis, Membrane Assembly and Repair, and Parasite ReplicationZIAHD001415 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ZIMMERBERG, JOSHUA · 2009 to 2025
$26.0M
6 · The paper itself

Abstract

Morphological plasticity of biological membrane is critical for cellular life, as cells need to quickly rearrange their membranes. Yet, these rearrangements are constrained in two ways. First, membrane transformations may not lead to undesirable mixing of, or leakage from, the participating cellular compartments. Second, membrane systems should be metastable at large length scales, ensuring the correct function of the particular organelle and its turnover during cellular division. Lipids, through their ability to exist with many shapes (polymorphism), provide an adequate construction material for cellular membranes. They can self-assemble into shells that are very flexible, albeit hardly stretchable, which allows for their far-reaching morphological and topological behaviors. In this article, we will discuss the importance of lipid polymorphisms in the shaping of membranes and its role in controlling cellular membrane morphology.

Indexed as

Cell MembraneCell ShapeLipid BilayersMembrane LipidsMembrane ProteinsLipid BilayersMembrane LipidsMembrane Proteins

Identifiers

PMID21646378
PMCPMC3220359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.