ArticleNucleic acids research2011
The Gene3D Web Services: a platform for identifying, annotating and comparing structural domains in protein sequences.
Article in Nucleic acids research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- The language of the protein universe.Current opinion in genetics & development · 2015Review
- Evolutionary history of the TBP-domain superfamily.Nucleic acids research · 2013Article
- SIFTS: Structure Integration with Function, Taxonomy and Sequences resource.Nucleic acids research · 2013Article
- ProtoNet 6.0: organizing 10 million protein sequences in a compact hierarchical family tree.Nucleic acids research · 2012Article
- Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis.Nucleic acids research · 2012Article
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Authors and funding
5 authors.
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Abstract
The Gene3D structural domain database provides domain annotations for 7 million proteins, based on the manually curated structural domain superfamilies in CATH. These annotations are integrated with functional, genomic and molecular information from external resources, such as GO, EC, UniProt and the NCBI Taxonomy database. We have constructed a set of web services that provide programmatic access to this integrated database, as well as the Gene3D domain recognition tool (Gene3DScan) and protein sequence annotation pipeline for analysing novel protein sequences. Example queries include retrieving all curated GO terms for a domain superfamily or all the multi-domain architectures for the human genome. The services can be accessed using simple HTTP calls and are able to return results in a range of formats for quick downloading and easy parsing, graphical rendering and data storage. Hence, they provide a simple, but flexible means of integrating domain annotations and associated data sets into locally run pipelines and analysis software. The services can be found at http://gene3d.biochem.ucl.ac.uk/WebServices/.
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