Evidence map›Paper›PMID 21646013›Full record

ReviewCurrent opinion in neurobiology2011

Neuromodulation and flexibility in Central Pattern Generator networks.

Ronald M Harris-Warrick

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
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  9. Article
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  11. Modulation by Neuropeptides with Overlapping Targets Results in Functional Overlap in Oscillatory Circuit Activation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  12. Article
  13. Article
  14. A CPG-Based Versatile Control Framework for Metameric Earthworm-Like Robotic Locomotion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Recording from Snail Motor Nerves to Investigate Central Pattern Generation.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2022
    Article
  19. Review
  20. Neuronal Switching between Single- and Dual-Network Activity via Modulation of Intrinsic Membrane Properties.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ronald M Harris-WarrickDepartment of Neurobiology and Behavior, Seeley G. Mudd Hall, Cornell University, Ithaca, NY 14853, USA. rmh4@cornell.edu

Funding

NEUROTRANSMITTERS, NEUROMODULATORS &MOTOR SYSTEMSR01NS017323 · NINDS · CORNELL UNIVERSITY ITHACA · PI HARRIS-WARRICK, RONALD M · 1985 to 2017
$3.3M
Neurotransmitters, Neuromodulators and Motor SystemsR37NS017323 · NINDS · CORNELL UNIVERSITY · PI HARRIS-WARRICK, RONALD M · 2006 to 2012
$2.9M
The rodent central pattern generator for locomotionR01NS057599 · NINDS · CORNELL UNIVERSITY · PI HARRIS-WARRICK, RONALD M · 2009 to 2010
$692k
Neurotransmitters, Neuromodulators and Motor SystemsR56NS017323 · NINDS · CORNELL UNIVERSITY · PI HARRIS-WARRICK, RONALD M · 2013 to 2013
$387k
NINDS NIH HHS R01 NS017323NINDS NIH HHS R01 NS057599NINDS NIH HHS R37 NS017323NINDS NIH HHS R56 NS017323
6 · The paper itself

Abstract

Central Pattern Generator (CPG) networks, which organize rhythmic movements, have long served as models for neural network organization. Modulatory inputs are essential components of CPG function: neuromodulators set the parameters of CPG neurons and synapses to render the networks functional. Each modulator acts on the network by many effects which may oppose one another; this may serve to stabilize the modulated state. Neuromodulators also determine the active neuronal composition in the CPG, which varies with state changes such as locomotor speed. The pattern of gene expression which determines the electrophysiological personality of each CPG neuron is also under modulatory control. It is not possible to model the function of neural networks without including the actions of neuromodulators.

Indexed as

Models, NeurologicalPeriodicityAction PotentialsAnimalsHumansIon ChannelsMotor NeuronsMovementNerve NetNeural PathwaysNeurotransmitter AgentsIon ChannelsNeurotransmitter Agents

Identifiers

PMID21646013
PMCPMC3171584

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.