Evidence map›Paper›PMID 21645388›Full record

ArticleBMC infectious diseases2011

Patient acceptance of universal screening for hepatitis C virus infection.

Phillip O Coffin, Anne M Stevens, John D Scott, Joanne D Stekler, Matthew R Golden

Abstract read
In one paragraph

Article in BMC infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Recommendations on hepatitis C screening for adults.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Guideline
  2. Review
  3. Article
  4. Routine screening of emergency admissions at risk of chronic hepatitis (SEARCH) identifies and links hepatitis B cases to care.Liver international : official journal of the International Association for the Study of the Liver · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Hepatitis C screening: getting it right.Hepatology (Baltimore, Md.) · 2013
    Article
  11. Best strategies for global HCV eradication.Liver international : official journal of the International Association for the Study of the Liver · 2013
    Review
  12. Screening for hepatitis C virus infection.Gastroenterology & hepatology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Phillip O CoffinDivision of Allergy and Infectious Diseases, University of Washington, Seattle WA, USA. pcoffin@uw.edu
Anne M Stevens
John D Scott
Joanne D Stekler
Matthew R Golden

Funding

VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
NIAID NIH HHS 5T32AI007140-33
6 · The paper itself

Abstract

backgroundIn the United States, about 70% of 2.9-3.7 million people with hepatitis C (HCV) are unaware of their infection. Although universal screening might be a cost-effective way to identify infections, prevent morbidity, and reduce transmission, few efforts have been made to determine patient opinions about new approaches to screening.

methodsWe surveyed 200 patients in August 2010 at five outpatient clinics of a major public urban medical center in Seattle, WA, with an 85.8% response rate.

resultsThe sample was 55.3% women, median 47 years of age, and 56.3% white and 32.7% African or African-American; 9.5% and 2.5% reported testing positive for HCV and HIV, respectively. The vast majority of patients supported universal screening for HCV. When presented with three options for screening, 48% preferred universal testing without being informed that they were being tested or provided with negative results, 37% preferred testing with the chance to "opt-out" of being tested and without being provided with negative results, and 15% preferred testing based on clinician judgment. Results were similar for HIV screening.

conclusionsPatients support universal screening for HCV, even if that screening involves testing without prior consent or the routine provision of negative test results. Current screening guidelines and procedures should be reconsidered in light of patient priorities.

Indexed as

Patient Acceptance of Health CareAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHepacivirusHepatitis CHumansMaleMass ScreeningMiddle AgedUrban HealthWashingtonYoung Adult

Identifiers

PMID21645388
PMCPMC3118145

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.