Evidence map›Paper›PMID 21644139›Full record

ArticleJournal of clinical and experimental neuropsychology2011

Cognitive profiles in persons with chronic schizophrenia.

Sharron E Dawes, Dilip V Jeste, Barton W Palmer

Abstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A cognitive-emotional biomarker for predicting remission with antidepressant medications: a report from the iSPOT-D trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
    Trial
  5. Article
  6. Article
  7. Article
  8. The definition and measurement of heterogeneity.Translational psychiatry · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Beyond Lumping and Splitting: A Review of Computational Approaches for Stratifying Psychiatric Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2016
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sharron E DawesDepartment of Psychiatry, University of California, San Diego, La Jolla, USA.
Dilip V Jeste
Barton W Palmer

Funding

Research Methods CoreP30MH080002 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JESTE, DILIP V. · 2007 to 2011
$9.6M
FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
CAPACITY TO CONSENT TO RESEARCH ON PSYCHOSISR01MH064722 · NIMH · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI PALMER, BARTON W. · 2002 to 2013
$3.1M
NIH HHS P30 NH080002NIMH NIH HHS P30 MH080002NIMH NIH HHS R01 MH064722NIMH NIH HHS T32 MH019934PHS HHS 64722
6 · The paper itself

Abstract

Cognitive heterogeneity has been a key barrier to clarifying the neuropathologic underpinnings of schizophrenia. We used an idiographic method for cluster analysis of neuropsychological data from 144 middle-aged and older people with schizophrenia to characterize and group the patterns of relative (within-person) profiles of cognitive strength and weakness. Results indicated a 5-cluster solution as most appropriate, with relatively even distribution across the 5 clusters in terms of the proportion of patients in each cluster. Cognitive subtyping may be useful in imaging and genetic research on schizophrenia, as well as having practical utility in treatment planning and cognitive rehabilitation.

Indexed as

Schizophrenic PsychologyAdultAgedAuditory PerceptionChronic DiseaseCluster AnalysisCognition DisordersComprehensionFemaleHumansLearningMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesSchizophrenia

Identifiers

PMID21644139
PMCPMC3221409

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.