Evidence map›Paper›PMID 21644037›Full record

ArticleActa neuropathologica2011

A harmonized classification system for FTLD-TDP pathology.

Ian R A Mackenzie, Manuela Neumann, Atik Baborie, Deepak M Sampathu, Daniel Du Plessis, Evelyn Jaros, Robert H Perry, John Q Trojanowski, David M A Mann, Virginia M Y Lee

Abstract readLetterComment
In one paragraph

Article in Acta neuropathologica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 574 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
574citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

574 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Astrocyte-Predominant Tau Pathology in a Patient With VCP R191Q Variant.Neuropathology : official journal of the Japanese Society of Neuropathology · 2026
    Article
  4. TMEM106B is a selective modulator of TDP-43 pathology in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Digital seed amplification assay for TDP-43 aggregate quantification in CSF.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  16. Article
  17. Decoding neurodegeneration one cell at a time.The Journal of clinical investigation · 2026
    Review
  18. ALS and Huntington Disease: Unraveling the Connections between TDP-43 and Huntingtin.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  19. Article
  20. Article

514 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Ian R A Mackenzie
Manuela Neumann
Atik Baborie
Deepak M Sampathu
Daniel Du Plessis
Evelyn Jaros
Robert H Perry
John Q Trojanowski
David M A Mann
Virginia M Y Lee

Funding

Transgenic Mouse Models of Tau PathologiesP01AG017586 · NIA · UNIVERSITY OF PENNSYLVANIA · PI LEE, VIRGINIA M · 2000 to 2021
$37.3M
UPenn ADCC Biomarker CoreP30AG010124 · NIA · UNIVERSITY OF PENNSYLVANIA · PI XIE, SHARON XIANGWEN · 1991 to 2020
$35.1M
Examining neuronal resilience in a mouse model of sporadic ALSR01NS110688 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI LEE, VIRGINIA M · 2019 to 2023
$1.8M
NIA NIH HHS AG-10124NIA NIH HHS AG-17586NIA NIH HHS P01 AG017586NIA NIH HHS P30 AG010124NINDS NIH HHS R01 NS110688Wellcome Trust 089701
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PhenotypeAnimalsAntibodies, MonoclonalDementiaFemaleFrontal LobeHumansInclusion BodiesMaleTemporal LobeUbiquitinAntibodies, MonoclonalUbiquitin

Identifiers

PMID21644037
PMCPMC3285143

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.