ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2011
Exercise-induced laryngeal obstruction: natural history and effect of surgical treatment.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ipratropium Bromide (Atrovent®) Used to Treat Exercise Induced Laryngeal Obstruction (EILO). An Open Label Pilot Study
Exercise Induced Laryngeal Obstruction; a Randomized Controlled Treatment Trial
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Exercise induced laryngeal obstruction: a review of diagnosis and management.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Pooled it
- Effects of Exercise-Induced Laryngeal Obstruction in Adolescents: A Qualitative Study.American journal of speech-language pathology · 2024Article
- Prevalence and characterisation of exercise-induced laryngeal obstruction in patients with exercise-induced dyspnoea.The Journal of laryngology and otology · 2024Article
- Laryngeal response to high-intensity exercise in healthy athletes.BMJ open sport & exercise medicine · 2024Article
- The Clinical Utility of Continuous Laryngoscopy During Exercise: A Report of Two Cases.Cureus · 2023Article
- Management of comorbidities in difficult and severe asthma.Breathe (Sheffield, England) · 2023Review
- A longitudinal follow-up of continuous laryngoscopy during exercise test scores in athletes irrespective of laryngeal obstruction, respiratory symptoms, and intervention.BMC sports science, medicine & rehabilitation · 2023Article
- Therapy Outcomes for Teenage Athletes With Exercise-Induced Laryngeal Obstruction.American journal of speech-language pathology · 2023Article
- Article
- Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'.British journal of sports medicine · 2022Review
- Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Characteristics and impact of exercise-induced laryngeal obstruction: an international perspective.ERJ open research · 2021Article
- Life-threatening laryngeal injury in Elite Rugby Union: Prevention and management laryngeal trauma in rugby.Clinical case reports · 2021Article
- Is the healthy respiratory system built just right, overbuilt, or underbuilt to meet the demands imposed by exercise?Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Pediatric Dysfunctional Breathing: Proposed Components, Mechanisms, Diagnosis, and Management.Frontiers in pediatrics · 2020Review
- An unusual cause of exertional dyspnea in a 55 years old man.Respiratory medicine case reports · 2020Article
- Laryngeal Electromyography and Botulinum Toxin Injection in Exercise-Induced Laryngeal Obstruction.Movement disorders clinical practice · 2019Article
- A systematic review of surgical treatment for supraglottic exercise-induced laryngeal obstruction.Laryngoscope investigative otolaryngology · 2019Review
- Exercise Induced Laryngeal Obstruction in Humans and Equines. A Comparative Review.Frontiers in physiology · 2019Article
- Severe Exercise-Induced Laryngeal Obstruction Treated With Supraglottoplasty.Frontiers in surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current follow-up study concerning the supraglottic type of exercise-induced laryngeal obstruction (EILO) was performed to reveal the natural history of supraglottic EILO and compare the symptoms, as well as the laryngeal function in conservatively versus surgically treated patients. A questionnaire-based survey was conducted 2-5 years after EILO was diagnosed by a continuous laryngoscopy exercise (CLE) test in 94 patients with a predominantly supraglottic obstruction. Seventy-one patients had been treated conservatively and 23 with laser supraglottoplasty. The questionnaire response rate was 70 and 100% in conservatively treated (CT) and surgically treated (ST) patients, respectively. A second CLE test was performed in 14 CT and 19 ST patients. A visual analogue scale on symptom severity indicated improvements in both the groups, i.e. mean values (± standard deviations) declined from 73 (20) to 53 (26) (P < 0.001) in the CT group and from 87 (26) to 25 (27) (P < 0.001) in the ST group. At follow-up, ST patients reported lower scores regarding current level of complaints, and higher ability to perform exercise, as well as to push themselves physically, all compared to CT patients (P < 0.001). CLE scores were normalized in 3 of 14 (21%) CT and 16 of 19 (84%) ST patients (Z = -3.6; P < 0.001). In conclusion, symptoms of EILO diagnosed in adolescents generally decreased during 2-5 years follow-up period but even more after the surgical treatment. Patients with supraglottic EILO may benefit from supraglottoplasty both as to laryngeal function and symptom relief.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.