ArticleMolecular biology reports2012
Molecular characterization of CART, AgRP, and MC4R genes and their expression with fasting and re-feeding in common carp (Cyprinus carpio).
Article in Molecular biology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 73 citations in OpenAlex.
- Neural Melanocortin Receptors in Fish: Insights into Growth Regulation and Aquaculture Advancement.Biomolecules · 2026Review
- Cocaine- and amphetamine-regulated transcripts in two percomorphs: evolutionary conservation and energy-status dependent responses.Frontiers in endocrinology · 2026Article
- Neuropeptide Y receptor Y8b (Journal of Zhejiang University. Science. B · 2024Article
- Effects of different acute stressors on the regulation of appetite genes in the carp (Royal Society open science · 2023Article
- Improved Growth and High Inheritance of Melanocortin-4 Receptor (mc4r) Mutation in CRISPR/Cas-9 Gene-Edited Channel Catfish, Ictalurus punctatus.Marine biotechnology (New York, N.Y.) · 2022Article
- The neuropeptide Y receptor gene repository, phylogeny and comparative expression in allotetraploid common carp.Scientific reports · 2022Article
- MRAP2 Interaction with Melanocortin-4 Receptor in SnakeHead (Biomolecules · 2021Article
- The Melanocortin System in Atlantic Salmon (Frontiers in neuroanatomy · 2020Article
- Three forms of cocaine- and amphetamine-regulated transcript may be involved in food intake regulation in gibel carp (Carassius auratus gibelio).Fish physiology and biochemistry · 2019Article
- Nutrient Regulation of Endocrine Factors Influencing Feeding and Growth in Fish.Frontiers in endocrinology · 2019Review
- One evidence of cocaine- and amphetamine-regulated transcript (CART) has the bidirectional effects on appetite in Siberian sturgeon (Acipenser baerii).Fish physiology and biochemistry · 2018Article
- Effect of growth hormone overexpression on gastric evacuation rate in coho salmon.Fish physiology and biochemistry · 2018Article
- Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish.Scientific reports · 2017Article
- Appetite-Controlling Endocrine Systems in Teleosts.Frontiers in endocrinology · 2017Review
- Ya-fish (Schizothorax prenanti) spexin: identification, tissue distribution and mRNA expression responses to periprandial and fasting.Fish physiology and biochemistry · 2016Article
- The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge.Frontiers in neuroscience · 2016Review
- Melanocortin-4 receptor (MC4R) polymorphisms are associated with growth and meat quality traits in sheep.Molecular biology reports · 2014Article
- Article
- The effects of amphetamine injections on feeding behavior and the brain expression of orexin, CART, tyrosine hydroxylase (TH) and thyrotropin releasing hormone (TRH) in goldfish (Carassius auratus).Fish physiology and biochemistry · 2013Article
- A consensus linkage map provides insights on genome character and evolution in common carp (Cyprinus carpio L.).Marine biotechnology (New York, N.Y.) · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cocaine and amphetamine-regulated transcript (CART), agouti-related proteins (AgRP) and Melanocortin 4 Receptor (MC4R) involves in the control of appetite. The genes were cloned and characterized, and their regulation was studied in common carp. The CARTI and CARTII genes encode 117- and 120-amino acids, respectively. The AgRP-1 and AgRP-2 genes encode 128- and 136-amino acids, respectively. CARTI was principally expressed in the brain, eye and ovary, while CARTII was highly expressed in the brain. AgRP-1 was strongly expressed in the brain, intestine, testis and eye, while AgRP-2 was highly expressed only in the gill and eye. The MC4R gene, encoding 326-amino acids, was mainly expressed in the brain testis, pituitary and eye. Phylogenetic analysis had been conducted which implied that both CARTI/CARTII and AgRP-1/AgRP-2 might derived from gene duplication events during genome evolution of common carp. CART, AgRP and MC4R gene expression in brain were decreased after fasting treatment and increased sharply after refeeding comparing with normal fed controls, which suggested that CART, AgRP and MC4R are involved in appetite regulation in common carp.
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