ArticleDigestive diseases and sciences2011
Risk of functional gastrointestinal disorders in U.S. military following self-reported diarrhea and vomiting during deployment.
Article in Digestive diseases and sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults.The American journal of gastroenterology · 2016Guideline
- Effectiveness of rifaximin and fluoroquinolones in preventing travelers' diarrhea (TD): a systematic review and meta-analysis.Systematic reviews · 2012Pooled it
- Vitamin D Deficiency (VDD) and Benefits of Supplementation in Veterans with IBS-D.Diagnostics (Basel, Switzerland) · 2023Article
- Microbiome and Its Role in Irritable Bowel Syndrome.Digestive diseases and sciences · 2020Review
- Chronic Gastrointestinal and Joint-Related Sequelae Associated with Common Foodborne Illnesses: A Scoping Review.Foodborne pathogens and disease · 2020Article
- The Relation between Dietary Patterns and Functional Gastrointestinal Disorders among Iranian Military Men.Advanced biomedical research · 2019Article
- Travelers' diarrhea: update on the incidence, etiology and risk in military and similar populations - 1990-2005 versus 2005-2015, does a decade make a difference?Tropical diseases, travel medicine and vaccines · 2019Article
- The Risk of Chronic Gastrointestinal Disorders Following Acute Infection with Intestinal Parasites.Frontiers in microbiology · 2018Article
- A review of antibiotic prophylaxis for traveler's diarrhea: past to present.Tropical diseases, travel medicine and vaccines · 2018Review
- Effects of Psychological, Environmental and Physical Stressors on the Gut Microbiota.Frontiers in microbiology · 2018Review
- Guidelines for the prevention and treatment of travelers' diarrhea: a graded expert panel report.Journal of travel medicine · 2017Review
- The Epidemiology of Irritable Bowel Syndrome in the US Military: Findings from the Millennium Cohort Study.The American journal of gastroenterology · 2016Article
- Infectious Gastroenteritis as a Risk Factor for Tropical Sprue and Malabsorption: A Case-Control Study.Digestive diseases and sciences · 2015Article
- Combination vaccines against diarrheal diseases.Human vaccines & immunotherapeutics · 2015Review
- Gastrointestinal problems in modern wars: clinical features and possible mechanisms.Military Medical Research · 2015Article
- Role of gut pathogens in development of irritable bowel syndrome.The Indian journal of medical research · 2014Review
- Psychological disorders in gastrointestinal disease: epiphenomenon, cause or consequence?Annals of gastroenterology · 2014Article
- The analysis of factors associated with progression of isolated terminal ileal lesions.PloS one · 2014Article
- A case-control study of incident rheumatological conditions following acute gastroenteritis during military deployment.BMJ open · 2013Article
- Irritable bowel syndrome in the UK military after deployment to Iraq: what are the risk factors?Social psychiatry and psychiatric epidemiology · 2013Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMilitary personnel are frequently deployed to regions of the world with high travelers' diarrhea (TD) rates. Pathogens associated with TD have been linked to several post-infectious sequelae, including functional gastrointestinal disorders (FGD), such as irritable bowel syndrome (IBS) and functional dyspepsia. Furthermore, stress associated with deployment may potentiate the increased FGD risk.
aimWe sought to assess whether self-reported diarrhea, vomiting, and stressors during deployment were associated with increased FGD risk.
methodsUsing active duty military medical encounter data from the Defense Medical Surveillance System (DMSS), we conducted a matched case-control study to assess the odds of FGD (IBS, functional constipation, functional diarrhea, dyspepsia) following self-reported diarrhea or vomiting during deployment. Only first-time deployers with detailed self-reporting of deployment-related exposures from 2008 and 2009 were included. Univariate and multivariate analyses were performed.
resultsA total of 129 cases of FGD were identified, with the following distribution: constipation (n = 67), dyspepsia (n = 15), IBS (n = 22), and overlapping disorders (n = 25). Diarrhea and/or vomiting during deployment were significantly associated with the development of FGD. Other demographic factors were also associated with variable risk. We found no consistent effect of war-related stressors or non-combat-related correlates of stress.
conclusionsDeployment-related TD is common in deployed military personnel and is associated with an increased risk of several FGD. When considering effective countermeasures and mitigation strategies, both the acute effects and chronic sequelae of enteric infections should be considered. Increased emphasis on existing and novel primary prevention strategies are needed, as well as outcome studies among those developing these conditions.
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