ReviewMicrobial ecology2011
The Salmonella enterica pan-genome.
Review in Microbial ecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
114 citing papers in PubMed.
- Genomic architecture of antimicrobial resistance and mobile genetic elements inMicrobiology spectrum · 2026Article
- Genomic analysis of antibiotic resistance and virulence factors in the uropathogenMicrobial genomics · 2026Article
- XtractPAV: an automated pipeline for identifying presence-absence variations across multiple genomes.BMC genomics · 2026Article
- Article
- Deletion of theVirulence · 2025Article
- A machine learning approach to predict strain-specific phage-host interactions.Scientific reports · 2025Article
- Genomic Markers Distinguishing Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2025Article
- Worldwide Population Dynamics ofGenes · 2025Article
- Beyond H37Rv:Frontiers in microbiology · 2025Review
- Comparative genomic profiling of virulence genes in human clinical isolates ofFrontiers in cellular and infection microbiology · 2025Article
- Rapid assessment of clinical severity for salmonellosis cases via protein family domain analysis and machine learning.Academia molecular biology and genomics · 2025Article
- Heterogeneity ofInfection and immunity · 2024Article
- Unveiling a Comprehensive Multi-epitope Subunit Vaccine Strategy Against Salmonella subsp. enterica: Bridging Core, Subtractive Proteomics, and Immunoinformatics.Cell biochemistry and biophysics · 2024Article
- Article
- Diversification of gene content in theMicrobiology spectrum · 2024Article
- Genome sequencing and analysis of Salmonella enterica subsp. enterica serotype Enteritidis PT4 578: insights into pathogenicity and virulence.Access microbiology · 2024Article
- Step-by-Step Bacterial Genome Comparison.Methods in molecular biology (Clifton, N.J.) · 2024Article
- For Someone, You Are the Whole World: Host-Specificity ofInternational journal of molecular sciences · 2023Article
- Article
- Comparative Genomic Analysis Discloses Differential Distribution of Antibiotic Resistance Determinants between Worldwide Strains of the Emergent ST213 Genotype ofAntibiotics (Basel, Switzerland) · 2022Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salmonella enterica is divided into four subspecies containing a large number of different serovars, several of which are important zoonotic pathogens and some show a high degree of host specificity or host preference. We compare 45 sequenced S. enterica genomes that are publicly available (22 complete and 23 draft genome sequences). Of these, 35 were found to be of sufficiently good quality to allow a detailed analysis, along with two Escherichia coli strains (K-12 substr. DH10B and the avian pathogenic E. coli (APEC O1) strain). All genomes were subjected to standardized gene finding, and the core and pan-genome of Salmonella were estimated to be around 2,800 and 10,000 gene families, respectively. The constructed pan-genomic dendrograms suggest that gene content is often, but not uniformly correlated to serotype. Any given Salmonella strain has a large stable core, whilst there is an abundance of accessory genes, including the Salmonella pathogenicity islands (SPIs), transposable elements, phages, and plasmid DNA. We visualize conservation in the genomes in relation to chromosomal location and DNA structural features and find that variation in gene content is localized in a selection of variable genomic regions or islands. These include the SPIs but also encompass phage insertion sites and transposable elements. The islands were typically well conserved in several, but not all, isolates--a difference which may have implications in, e.g., host specificity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.