Evidence map›Paper›PMID 21643667›Full record

ArticleTropical animal health and production2012

Psoroptes cuniculi induced oxidative imbalance in rabbits and its alleviation by using vitamins A, D3, E, and H as adjunctive remedial.

Shanker Kumar Singh, Umesh Dimri, Mahesh Chandra Sharma, Devendra Swarup, Mritunjay Kumar, Ramesh Tiwary

Abstract read
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In one paragraph

Article in Tropical animal health and production, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. ChronicVeterinary sciences · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Control and therapeutic management of bovine tropical theileriosis in crossbred cattle.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016
    Article
  7. Clinico-pathological and therapeutic evaluation of Black Bengal goats (Capra hircus) infested with Psoroptes cuniculi mange.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016
    Article
  8. Salvage of Theileria infected calves with clinical manifestation of exophthalmia.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2015
    Article
  9. Article
  10. Efficacy of doramectin in Trixacarus caviae infestation in guinea pigs (Cavia porcellus).Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2013
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shanker Kumar SinghDivision of Medicine, Indian Veterinary Research Institute, Izatnagar-243 122, Bareilly, UP, India. pshankervet@gmail.com
Umesh Dimri
Mahesh Chandra Sharma
Devendra Swarup
Mritunjay Kumar
Ramesh Tiwary
Indian Veterinary Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oxidant/antioxidant balance of rabbits naturally infected with Psoroptes cuniculi and treated with ivermectin +/- vitamins A, D(3), E, and H supplementation was investigated. Two groups of seven mixed ♂ and ♀, 6-to-8 month-old New Zealand White rabbits, diagnosed Psoroptes mites-positive by skin scraping examination and seven clinically healthy control rabbits were examined. Blood samples were obtained on day 0 and at 28 days post-therapy to determine oxidative stress indices. On day 0, the levels of lipid peroxides were significantly higher (P ≤ 0.01) in the Psoroptes-infected rabbits compared with the healthy controls while those of reduced glutathione and the activities of the antioxidant enzymes glutathione peroxidase, glutathione-S-transferase, catalase, and superoxide dismutase were significantly lower (P ≤ 0.01). Vitamin supplementation of the ivermectin-treated rabbits revealed both faster clinical (14 days) and parasitological (10 days) recovery. It was concluded that significant alteration of oxidant/antioxidant balance is a factor in the pathogenesis of P. cuniculi infestation of rabbits, and recovery can be enhanced by combining ivermectin treatment with vitamin A, D(3,) E, and H supplementation.

Indexed as

Adjuvants, PharmaceuticAnimalsAntiparasitic AgentsBiomarkersBlood Chemical AnalysisDrug CombinationsFemaleInjections, IntramuscularInjections, SubcutaneousIvermectinMaleMite InfestationsOxidative StressPsoroptidaeRabbitsVitaminsAdjuvants, PharmaceuticAntiparasitic AgentsBiomarkersDrug CombinationsIvermectinVitamins

Identifiers

PMID21643667
OpenAlexW2008012194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.