ArticleNature methods2011
Single-tube linear DNA amplification (LinDA) for robust ChIP-seq.
Article in Nature methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed.
- scNanoSeq-CUT&Tag: a single-cell long-read CUT&Tag sequencing method for efficient chromatin modification profiling within individual cells.Nature methods · 2024Article
- Article
- Three-dimensional molecular cartography of human cerebral organoids revealed by double-barcoded spatial transcriptomics.Cell reports methods · 2023Article
- 2cChIP-seq and 2cMeDIP-seq: The Carrier-Assisted Methods for Epigenomic Profiling of Small Cell Numbers or Single Cells.International journal of molecular sciences · 2022Article
- nMOWChIP-seq: low-input genome-wide mapping of non-histone targets.NAR genomics and bioinformatics · 2022Article
- Single-Cell Factor Localization on Chromatin using Ultra-Low Input Cleavage Under Targets and Release using Nuclease.Journal of visualized experiments : JoVE · 2022Article
- Phase separation in epigenetics and cancer stem cells.Frontiers in oncology · 2022Review
- Transcription factor chromatin profiling genome-wide using uliCUT&RUN in single cells and individual blastocysts.Nature protocols · 2021Article
- aFARP-ChIP-seq, a convenient and reliable method for genome profiling in as few as 100 cells with a capability for multiplexing ChIP-seq.Epigenetics · 2019Article
- FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical regulation.BMC biology · 2019Article
- Terminal transfer amplification and sequencing for high-efficiency and low-bias copy number profiling of fragmented DNA samples.Protein & cell · 2019Article
- High-throughput ChIPmentation: freely scalable, single day ChIPseq data generation from very low cell-numbers.BMC genomics · 2019Article
- Genome-wide histone modification profiling of inner cell mass and trophectoderm of bovine blastocysts by RAT-ChIP.PloS one · 2019Article
- LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.Genome biology · 2018Article
- Microfluidic Low-Input Fluidized-Bed Enabled ChIP-seq Device for Automated and Parallel Analysis of Histone Modifications.Analytical chemistry · 2018Article
- Low-input and multiplexed microfluidic assay reveals epigenomic variation across cerebellum and prefrontal cortex.Science advances · 2018Article
- Integrating ChIP-seq with other functional genomics data.Briefings in functional genomics · 2018Review
- ChIP-ping the branches of the tree: functional genomics and the evolution of eukaryotic gene regulation.Briefings in functional genomics · 2018Review
- Cell Type-Specific Survey of Epigenetic Modifications by Tandem Chromatin Immunoprecipitation Sequencing.Scientific reports · 2018Article
- Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genome-wide profiling of transcription factors based on massive parallel sequencing of immunoprecipitated chromatin (ChIP-seq) requires nanogram amounts of DNA. Here we describe a high-fidelity, single-tube linear DNA amplification method (LinDA) for ChIP-seq and reChIP-seq with picogram DNA amounts obtained from a few thousand cells. This amplification technology will facilitate global analyses of transcription-factor binding and chromatin with very small cell populations, such as stem or cancer-initiating cells.
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