ArticleEukaryotic cell2011
Multiple roles of Ypd1 phosphotransfer protein in viability, stress response, and virulence factor regulation in Cryptococcus neoformans.
Article in Eukaryotic cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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Who cites it
30 citing papers in PubMed, 40 citations in OpenAlex.
- Conserved and rewired MAPK networks in human fungal pathogens.FEMS yeast research · 2026Review
- Signaling Pathways Regulating Dimorphism in Medically Relevant Fungal Species.Pathogens (Basel, Switzerland) · 2025Review
- Structural and functional insights underlying recognition of histidine phosphotransfer protein in fungal phosphorelay systems.Communications biology · 2024Article
- An array of signal-specific MoYpd1 isoforms determines full virulence in the pathogenic fungus Magnaporthe oryzae.Communications biology · 2024Article
- Genetic analysis of Hsp90 function in Cryptococcus neoformans highlights key roles in stress tolerance and virulence.Genetics · 2022Article
- Review
- A Radical Reimagining of Fungal Two-Component Regulatory Systems.Trends in microbiology · 2021Review
- Ypd1 Is an Essential Protein of the Major Fungal PathogenFrontiers in fungal biology · 2021Article
- Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins.BMC biochemistry · 2019Article
- Acetylation of BcHpt Lysine 161 RegulatesFrontiers in microbiology · 2019Article
- Stress-Activated Protein Kinases in Human Fungal Pathogens.Frontiers in cellular and infection microbiology · 2019Review
- Nutrient and Stress Sensing in Pathogenic Yeasts.Frontiers in microbiology · 2019Review
- Article
- Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity ofFrontiers in microbiology · 2018Article
- The phosphorelay signal transduction system in Candida glabrata: an in silico analysis.Journal of molecular modeling · 2017Article
- The yeasts phosphorelay systems: a comparative view.World journal of microbiology & biotechnology · 2017Review
- Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation.PLoS pathogens · 2017Article
- Fungal Histidine Phosphotransferase Plays a Crucial Role in Photomorphogenesis and Pathogenesis inFrontiers in chemistry · 2017Article
- Extended N-terminal region of the essential phosphorelay signaling protein Ypd1 from Cryptococcus neoformans contributes to structural stability, phosphostability and binding of calcium ions.FEMS yeast research · 2016Article
- A case for two-component signaling systems as antifungal drug targets.PLoS pathogens · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ypd1 is a key phosphorelay protein that controls eukaryotic two-component systems, but its function in Cryptococcus neoformans is not known. Here, we report that Ypd1 is required for the viability of C. neoformans via the Hog1 mitogen-activated protein kinase (MAPK) pathway but plays multiple cellular roles in both a Hog1-dependent and -independent manner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.