ArticleEnvironmental health perspectives2011
Acute respiratory inflammation in children and black carbon in ambient air before and during the 2008 Beijing Olympics.
Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
56 citing papers in PubMed, 5 syntheses or guidelines pooled it, 212 citations in OpenAlex.
- Individual-level interventions to reduce personal exposure to outdoor air pollution and their effects on people with long-term respiratory conditions.The Cochrane database of systematic reviews · 2021Pooled it
- The Effects of Fine Dust, Ozone, and Nitrogen Dioxide on Health.Deutsches Arzteblatt international · 2019Pooled it
- Interventions to reduce ambient particulate matter air pollution and their effect on health.The Cochrane database of systematic reviews · 2019Pooled it
- Epidemiology of childhood asthma in mainland China (1988-2014): A meta-analysis.Allergy and asthma proceedings · 2018Pooled it
- Fine Particulate Matter Concentrations in Urban Chinese Cities, 2005-2016: A Systematic Review.International journal of environmental research and public health · 2017Pooled it
- The effects of facemasks on airway inflammation and endothelial dysfunction in healthy young adults: a double-blind, randomized, controlled crossover study.Particle and fibre toxicology · 2018Trial
- The impacts of short-term exposure to noise and traffic-related air pollution on heart rate variability in young healthy adults.Journal of exposure science & environmental epidemiologyTrial
- Mega-Events, Air Pollution and Health Outcomes: A Systematic Review.Antioxidants (Basel, Switzerland) · 2026Review
- Trends and projections of PMFrontiers in public health · 2026Article
- Article
- Short-term, lagged association of airway inflammation, lung function, and asthma symptom score with PMEnvironmental epidemiology (Philadelphia, Pa.) · 2024Article
- Traffic-related air pollution, chronic stress, and changes in exhaled nitric oxide and lung function among a panel of children with asthma living in an underresourced community.The Science of the total environment · 2024Article
- Early-life exposure to residential black carbon and childhood cardiometabolic health.Environmental research · 2023Article
- Article
- Ambient Anthropogenic Carbons and Pediatric Respiratory Infections: A Case-Crossover Analysis in the Megacity Beijing.GeoHealth · 2023Article
- Biomarkers of particulate matter exposure in patients with chronic obstructive pulmonary disease: a systematic review.Journal of thoracic disease · 2023Review
- Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities.Innovation (Cambridge (Mass.)) · 2022Review
- Environmental Regulation and Chronic Conditions: Evidence from China's Air Pollution Prevention and Control Action Plan.International journal of environmental research and public health · 2022Article
- Arachidonic acid metabolism and inflammatory biomarkers associated with exposure to polycyclic aromatic hydrocarbons.Environmental research · 2022Article
- Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpidemiologic evidence for a causative association between black carbon (BC) and health outcomes is limited.
objectivesWe estimated associations and exposure-response relationships between acute respiratory inflammation in schoolchildren and concentrations of BC and particulate matter with an aerodynamic diameter of ≤ 2.5 μm (PM2.5) in ambient air before and during the air pollution intervention for the 2008 Beijing Olympics.
methodsWe measured exhaled nitric oxide (eNO) as an acute respiratory inflammation biomarker and hourly mean air pollutant concentrations to estimate BC and PM2.5 exposure. We used 1,581 valid observations of 36 subjects over five visits in 2 years to estimate associations of eNO with BC and PM2.5 according to generalized estimating equations with polynomial distributed-lag models, controlling for body mass index, asthma, temperature, and relative humidity. We also assessed the relative importance of BC and PM2.5 with two-pollutant models.
resultsAir pollution concentrations and eNO were clearly lower during the 2008 Olympics. BC and PM2.5 concentrations averaged over 0-24 hr were strongly associated with eNO, which increased by 16.6% [95% confidence interval (CI), 14.1-19.2%] and 18.7% (95% CI, 15.0-22.5%) per interquartile range (IQR) increase in BC (4.0 μg/m3) and PM2.5 (149 μg/m3), respectively. In the two-pollutant model, estimated effects of BC were robust, but associations between PM2.5 and eNO decreased with adjustment for BC. We found that eNO was associated with IQR increases in hourly BC concentrations up to 10 hr after exposure, consistent with effects primarily in the first hours after exposure.
conclusionsRecent exposure to BC was associated with acute respiratory inflammation in schoolchildren in Beijing. Lower air pollution levels during the 2008 Olympics also were associated with reduced eNO.
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