Evidence map›Paper›PMID 21640787›Full record

ArticleNeuroscience letters2011

Low-frequency H-reflex depression in trained human soleus after spinal cord injury.

Richard K Shields, Shauna Dudley-Javoroski, Preeti Deshpande Oza

Abstract readComparative Study
In one paragraph

Article in Neuroscience letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Comparison of Single-Session Dose Response Effects of Whole Body Vibration on Spasticity and Walking Speed in Persons with Spinal Cord Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2018
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  11. Fatigue modulates synchronous but not asynchronous soleus activation during stimulation of paralyzed muscle.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2013
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  12. Limb compressive load does not inhibit post activation depression of soleus H-reflex in indiviudals with chronic spinal cord injury.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2013
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  13. Limb segment load inhibits post activation depression of soleus H-reflex in humans.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Richard K ShieldsPhysical Therapy and Rehabilitation Science, The University of Iowa, Iowa City, IA, USA. richard-shields@uiowa.edu
Shauna Dudley-Javoroski
Preeti Deshpande Oza
University of Iowa · US

Funding

Neuro-Musculoskeletal Plasticity after SCIR01NR010285 · NINR · UNIVERSITY OF IOWA · PI SHIELDS, RICHARD K. · 2006 to 2010
$1.6M
Mechanical stress and skeletal plasticity after spinal cord injury in humansR01HD062507 · NICHD · UNIVERSITY OF IOWA · PI SHIELDS, RICHARD K. · 2010 to 2014
$1.5M
Novel Intervention to Influence Muscle Plasticity in Veterans with SCII01RX000149 · VA · IOWA CITY VA MEDICAL CENTER · PI SHIELDS, RICHARD K. · 2012 to 2014
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NICHD NIH HHS R01 HD062507NICHD NIH HHS R01HD062507NINR NIH HHS R01 NR010285NINR NIH HHS R01NR010285RRD VA I01 RX000149
6 · The paper itself

Abstract

After spinal cord injury (SCI), widespread reorganization occurs within spinal reflex systems. Regular muscle activity may influence reorganization of spinal circuitry after SCI. The purpose of this study is to investigate the effects of long-term soleus training on H-reflex depression in humans after SCI. Seven subjects with acute (<7 weeks) SCI (AC group) underwent testing of H-reflex depression at several frequencies of repetitive stimulation. Eight subjects (including 3 from AC) stimulated one soleus muscle daily, leaving the other leg as an untrained within-subject control. Trained limb H-reflexes were assessed during year 1 (TR1) and year 2 (TR2) of training. Untrained limbs were tested during year 2 (UN). H-reflex amplitude was lower at 1, 2 and 5 Hz than at 0.1 or 0.2 Hz (p<0.05). The pattern of depression differed between AC and UN (p<0.05), but not between TR2 and UN (p>0.05) despite significant adaptations in torque and fatigue resistance (p<0.05). Three subjects who began training very early after SCI retained H-reflex post activation depression, suggesting that early intervention of daily muscular activity may be important.

Indexed as

AdultCohort StudiesExercise TherapyFemaleH-ReflexHumansLong-Term Synaptic DepressionMaleMiddle AgedMuscle, SkeletalSpinal Cord InjuriesYoung Adult

Identifiers

PMID21640787
PMCPMC4034355
OpenAlexW2003978837

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.