Evidence map›Paper›PMID 21640698›Full record

ArticleAnalytical biochemistry2011

An inexpensive high-throughput nuclear magnetic resonance tube cleaning apparatus.

Bo Zhang, James Hodgson, Walter Hancock, Robert Powers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical biochemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bo ZhangDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
James Hodgson
Walter Hancock
Robert Powers
University of Nebraska–Lincoln · US

Funding

EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015468 · NCRR · UNIVERSITY OF NEBRASKA LINCOLN · PI PAUL, PREM S · 2000 to 2000
$2.0M
Citric acid cycle regulation of exopolysaccharide synthesis in staphylococciR01AI087668 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI SOMERVILLE, GREG ALAN · 2010 to 2013
$1.4M
Revealing Functions for Newly Discovered Proteins by FAST-NMRR21AI081154 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI POWERS, ROBERT · 2009 to 2010
$376k
NCRR NIH HHS C06 RR015468NCRR NIH HHS RR015468-01NIAID NIH HHS R01 AI087668NIAID NIH HHS R01AI087668NIAID NIH HHS R21 AI081154NIAID NIH HHS R21AI081154
6 · The paper itself

Abstract

Large-scale nuclear magnetic resonance (NMR) tube cleaning is currently a bottleneck in high-throughput NMR ligand affinity screens. Expensive alternatives include discarding the NMR tubes after a single use (~US $2-$8/tube), using commercial NMR tube cleaners (~$15,000), and abandoning NMR tubes for flow probe technology (~$75,000). Instead, we describe a relatively inexpensive (~$400) and easily constructed apparatus that can clean 180 NMR tubes per hour while using a modest amount of solvent. The application of this apparatus significantly shortens the time to recycle NMR tubes while avoiding cross-contamination and tube damage.

Indexed as

AcetoneMagnetic Resonance SpectroscopyMethanolNitric AcidRecyclingSodium BicarbonateSolventsWaterAcetoneMethanolNitric AcidSodium BicarbonateSolventsWater

Identifiers

PMID21640698
PMCPMC3138807
OpenAlexW2133374011

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.