Evidence map›Paper›PMID 21640212›Full record

ReviewBiochimica et biophysica acta

MicroRNAs and human retroviruses.

Laurent Houzet, Kuan-Teh Jeang

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. The role of miR-29 family in disease.Journal of cellular biochemistry · 2021
    Review
  9. Article
  10. Article
  11. Explaining Gene Expression Using Twenty-One MicroRNAs.Journal of computational biology : a journal of computational molecular cell biology · 2020
    Article
  12. Review
  13. Viral component of the human genome.Molecular biology · 2017
    Review
  14. Role of Different Subpopulations of CD8Frontiers in immunology · 2017
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laurent HouzetNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. lhouzet@mail.nih.gov
Kuan-Teh Jeang
National Institute of Allergy and Infectious Diseases · US

Funding

Molecular Mechanisms Of Human Immunodeficiency Virus Trans-regulatory ProteinsZIAAI000547 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI JEANG, KUAN-TEH · 2009 to 2013
$5.9M
Mechanisms of Cellular Transformation by HTLV-1ZIAAI001023 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI JEANG, KUAN-TEH · 2009 to 2013
$4.2M
Intramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI001023
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs that control a multitude of critical processes in mammalian cells. Increasing evidence has emerged that host miRNAs serve in animal cells to restrict viral infections. In turn, many viruses encode RNA silencing suppressors (RSS) which are employed to moderate the potency of the cell's miRNA selection against viral replication. Some viruses also encode viral miRNAs. In this review, we summarize findings from human immunodeficiency virus type 1 (HIV-1) and human T-cell leukemia virus type 1 (HTLV-1) that illustrate examples of host cell miRNAs that target the viruses, of RSS encoded by viruses, and of host cell miRNA profile changes that are seen in infected cells. This article is part of a Special Issue entitled: MicroRNAs in viral gene regulation.

Indexed as

Gene Expression Regulation, ViralHIV-1HumansHuman T-lymphotropic virus 1MicroRNAsModels, GeneticRetroviridaeRNA InterferenceRNA, ViralVirus ReplicationMicroRNAsRNA, Viral

Identifiers

PMID21640212
PMCPMC3177989
OpenAlexW2079602628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.