ReviewPediatric nephrology (Berlin, Germany)2012
Acute tubulointerstitial nephritis.
Review in Pediatric nephrology (Berlin, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 78 citations in OpenAlex.
- Prednisone in the treatment of tubulointerstitial nephritis in children.Pediatric nephrology (Berlin, Germany) · 2013Trial
- Viral tubulointerstitial nephritis in children: A narrative review with a focus on adenovirus.Pediatric nephrology (Berlin, Germany) · 2026Review
- Review
- A case of acute tubulointerstitial nephritis following the use of chenopodium album L.International journal of emergency medicine · 2024Article
- The diagnosis of acute interstitial nephritis caused by infection versus antibiotic-induced interstitial nephritis: a narrative review.Clinical kidney journal · 2024Review
- A case of tubulointerstitial nephritis mimicking acute focal bacterial nephritis. Lesson for the clinical nephrologist.Journal of nephrology · 2024Article
- Drugs in treating paediatric acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2023Review
- Favorable course of leptospirosis and hantavirus-induced acute tubulointerstitial nephritis under corticosteroid treatment.Pediatric nephrology (Berlin, Germany) · 2023Article
- Clinical Characteristics of Children With Acute Tubulointerstitial Nephritis: A Single-Center Experience.Cureus · 2023Article
- Diagnostic and Management Strategies of Tubulointerstitial Nephritis and Uveitis Syndrome (TINU): Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Clinical Manifestations and Laboratory Findings of Kawasaki Disease: Beyond the Classic Diagnostic Features.Medicina (Kaunas, Lithuania) · 2022Review
- Kidney involvement and histological findings in two pediatric COVID-19 patients.Pediatric nephrology (Berlin, Germany) · 2021Article
- Tubulointerstitial nephritis and uveitis syndrome following meningitis and systemic lymphadenopathy with persistent Toxoplasma immunoglobulin M: a case report.Journal of medical case reports · 2021Article
- Prednisolone treatment in acute interstitial nephritis (PRAISE) - protocol for the randomized controlled trial.BMC nephrology · 2021Article
- Elevation of erythrocyte sedimentation rate and C-reactive protein levels reflects renal interstitial inflammation in drug-induced acute tubulointerstitial nephritis.BMC nephrology · 2020Article
- Does fluoride cause the mysterious chronic kidney disease of multifactorial origin?Environmental geochemistry and health · 2020Review
- Acute tubulointerstitial nephritis following aciclovir treatment for chickenpox in children with nephrotic syndrome - a report of two cases.Central-European journal of immunology · 2020Article
- The Invisible Threat of Non-steroidal Anti-inflammatory Drugs for Kidneys.Frontiers in pediatrics · 2019Article
- Interstitial nephritis: Two pediatric cases with atypical radiological features.Radiology case reports · 2018Article
- Clinical features of acute kidney injury in patients with Kawasaki disease.World journal of clinical pediatrics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute tubulointerstitial nephritis (TIN) is a frequent cause of acute renal failure, characterised by the presence of inflammatory cell infiltrate in the interstitium of the kidney. Immuno-allergic reaction to certain medications, mainly non-steroidal anti-inflammatory drugs and antibiotics are by far the most important etiology for TIN today, but other situations such as infections, toxins, and vasculitis are known to induce TIN. Incidence of TIN is increasing, probably due to prescription habits and NSAID overuse, representing 3-7% of acute kidney injury in biopsies in children. Avoidance of the causal substance and rapid steroid therapy are hallmarks for patient care, but spontaneous initial recovery is very frequent and the general prognosis seems satisfactory. However, development of chronic TIN, without response to steroid or other immunosuppressive treatment, is possible. As the largest part of TIN is secondary to certain drugs, clear indications in particular for NSAID or antibiotics should be respected to reduce the number of TIN cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.