Evidence map›Paper›PMID 21638069›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2012

Cost of care for colorectal cancer in Ireland: a health care payer perspective.

L Tilson, L Sharp, C Usher, C Walsh, Whyte S, A O'Ceilleachair, C Stuart, B Mehigan, M John Kennedy, P Tappenden and 4 more

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Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Early Cost-effectiveness Analysis of Risk-Based Selection Strategies for Adjuvant Treatment in Stage II Colon Cancer: The Potential Value of Prognostic Molecular Markers.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
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  11. Survival and costs of colorectal cancer treatment and effects of changing treatment strategies: a model approach.The European journal of health economics : HEPAC : health economics in prevention and care · 2020
    Article
  12. Model-based evaluation of the cost effectiveness of 3Therapeutic advances in gastroenterology · 2020
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  13. Article
  14. Article
  15. Provider Costs of Treating Colorectal Cancer in Government Hospital of Malaysia.The Malaysian journal of medical sciences : MJMS · 2019
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  16. Article
  17. Economic burden of colorectal cancer in Iran in 2012.Medical journal of the Islamic Republic of Iran · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

L TilsonNational Centre for Pharmacoeconomics, St James's Hospital, Dublin 8, Ireland. ltilson@stjames.ie
L Sharp
C Usher
C Walsh
Whyte S
A O'Ceilleachair
C Stuart
B Mehigan
M John Kennedy
P Tappenden
J Chilcott
A Staines
H Comber
M Barry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveManagement options for colorectal cancer have expanded in recent years. We estimated average lifetime cost of care for colorectal cancer in Ireland in 2008, from the health care payer perspective.

methodA decision tree model was developed in Microsoft EXCEL. Site and stage-specific treatment pathways were constructed from guidelines and validated by expert clinical opinion. Health care resource use associated with diagnosis, treatment and follow-up were obtained from the National Cancer Registry Ireland (n=1,498 cancers diagnosed during 2004-2005) and three local hospital databases (n=155, 142 and 46 cases diagnosed in 2007). Unit costs for hospitalisation, procedures, laboratory tests and radiotherapy were derived from DRG costs, hospital finance departments, clinical opinion and literature review. Chemotherapy costs were estimated from local hospital protocols, pharmacy departments and clinical opinion. Uncertainty was explored using one-way and probabilistic sensitivity analysis.

resultsIn 2008, the average (stage weighted) lifetime cost of managing a case of colorectal cancer was €39,607. Average costs were 16% higher for rectal (€43,502) than colon cancer (€37,417). Stage I disease was the least costly (€23,688) and stage III most costly (€48,835). Diagnostic work-up and follow-up investigations accounted for 4 and 5% of total costs, respectively. Cost estimates were most sensitive to recurrence rates and prescribing of biological agents.

conclusionThis study demonstrates the value of using existing data from national and local databases in contributing to estimating the cost of managing cancer. The findings illustrate the impact of biological agents on costs of cancer care and the potential of strategies promoting earlier diagnosis to reduce health care resource utilisation and care costs.

Indexed as

Decision TreesAntineoplastic AgentsColorectal NeoplasmsHealth Care CostsHealth ExpendituresHealth ServicesHumansIrelandMass ScreeningNeoplasm StagingPalliative CareAntineoplastic Agents

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.