Evidence map›Paper›PMID 21637035›Full record

ArticleGut microbes

Current level of consensus on probiotic science--report of an expert meeting--London, 23 November 2009.

Ian Rowland, Lucio Capurso, Kevin Collins, John Cummings, Nathalie Delzenne, Olivier Goulet, Francisco Guarner, Philippe Marteau, Rémy Meier

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 108 citations in OpenAlex.

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  18. Probiotic characteristics ofSaudi journal of biological sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 6 countries.

Ian RowlandDepartment of Food and Nutritional Sciences, University of Reading, UK. i.rowland@reading.ac.uk
Lucio Capurso
Kevin Collins
John Cummings
Nathalie Delzenne
Olivier Goulet
Francisco Guarner
Philippe Marteau
Rémy Meier
Hôpital Lariboisière · FRHôpital Necker-Enfants Malades · FRKantonsspital Baselland · CHNinewells Hospital · GBOspedale San Filippo Neri · ITUCLouvain · BEUniversity College Cork · IEUniversity of Reading · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present paper summarizes the consensus views of a group of 9 European clinicians and scientists on the current state of scientific knowledge on probiotics, covering those areas where there is substantial evidence for beneficial effects and those where the evidence base is poor or inconsistent. There was general agreement that probiotic effects were species and often strain specific. The experts agreed that some probiotics were effective in reducing the incidence and duration of rotavirus diarrhoea in infants, antibiotic-associated diarrhoea in adults and, for certain probiotics, Clostridium difficile infections. Some probiotics are associated with symptomatic improvements in irritable bowel syndrome and alleviation of digestive discomfort. Probiotics can reduce the frequency and severity of necrotizing enterocolitis in premature infants and have been shown to regulate intestinal immunity. Several other clinical effects of probiotics, including their role in inflammatory bowel disease, atopic dermatitis, respiratory or genito-urinary infections or H.pylori adjuvant treatment were thought promising but inconsistent.

Indexed as

AdultBacteriaClostridium InfectionsDiarrheaDietDyspepsiaHumansImmunity, MucosalIncidenceInfantIntestinesIrritable Bowel SyndromeProbioticsRotavirus InfectionsTreatment Outcomediarrheaexpert consensusgut immunitygut microbiotainflammatory bowel diseasesirritable bowel syndromeprobioticsstrain specificity

Identifiers

PMID21637035
PMCPMC3056112
OpenAlexW1772983474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.