ArticleBiosensors & bioelectronics2011
Reversible thrombin detection by aptamer functionalized STING sensors.
Article in Biosensors & bioelectronics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Noninvasive methods to monitor dynamic single-cell events.Trends in cell biology · 2026Review
- Applications of Nanopipettes in Scanning Ion Conductance Microscopy for High-Spatial-Resolution Topographic Imaging and Sensing in Single Cells.ACS measurement science au · 2026Review
- Understanding Sensitivity in Nanoscale Sensing Devices.ACS measurement science au · 2025Article
- Solid-State Nanopores for Biomolecular Analysis and Detection.Advances in biochemical engineering/biotechnology · 2024Review
- In-Situ Fabrication of Electroactive CuBiosensors · 2023Article
- Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes.Molecular psychiatry · 2021Article
- Sensing with Nanopores and Aptamers: A Way Forward.Sensors (Basel, Switzerland) · 2020Review
- A glass nanopore ionic sensor for surface charge analysis.RSC advances · 2020Article
- Review
- Bioinspired integrated nanosystems based on solid-state nanopores: "Chemical science · 2017Article
- Smartphone Operated Signal Transduction by Ion Nanogating (STING) Amplifier for Nanopore Sensors: Design and Analytical Application.ACS sensors · 2016Article
- Oligonucleotide aptamers: A next-generation technology for the capture and detection of circulating tumor cells.Methods (San Diego, Calif.) · 2016Review
- Single Cell "Glucose Nanosensor" Verifies Elevated Glucose Levels in Individual Cancer Cells.Nano letters · 2016Article
- Article
- Aptamer based electrochemical sensors for emerging environmental pollutants.Frontiers in chemistry · 2014Review
- Nanopipette exploring nanoworld.Nano convergence · 2014Review
- Article
- Article
- Copper Sensing with a Prion Protein Modified Nanopipette.RSC advances · 2012Article
- Development of a Single Stranded DNA Aptamer as a Molecular Probe for LNCap Cells Using Cell-SELEX.Avicenna journal of medical biotechnologyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Signal Transduction by Ion NanoGating (STING) is a label-free technology based on functionalized quartz nanopipettes. The nanopipette pore can be decorated with a variety of recognition elements and the molecular interaction is transduced via a simple electrochemical system. A STING sensor can be easily and reproducibly fabricated and tailored at the bench starting from inexpensive quartz capillaries. The analytical application of this new biosensing platform, however, was limited due to the difficult correlation between the measured ionic current and the analyte concentration in solution. Here we show that STING sensors functionalized with aptamers allow the quantitative detection of thrombin. The binding of thrombin generates a signal that can be directly correlated to its concentration in the bulk solution.
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Registered trials
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