ArticleDrug and alcohol dependence2011
Strategies for characterizing complex phenotypes and environments: general and specific family environmental predictors of young adult tobacco dependence, alcohol use disorder, and co-occurring problems.
Article in Drug and alcohol dependence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 38 citations in OpenAlex.
- Exposure to sexually explicit media in early adolescence is related to risky sexual behavior in emerging adulthood.PloS one · 2020Trial
- College students' experiences, perceptions and management of health risks: a qualitative study in China.Frontiers in public health · 2026Article
- Combining family history and alcohol screening measures to identify emerging adults at risk of not being in education, employment, or training (NEET).Social psychiatry and psychiatric epidemiology · 2025Article
- General and Specific Risk and Protective Factors for Cigarette and Electronic Nicotine Delivery System (ENDS) Use.Prevention science : the official journal of the Society for Prevention Research · 2024Article
- Characteristics of Adolescents with and without a Family History of Substance Use Disorder from a Minority Cohort.Children (Basel, Switzerland) · 2024Article
- Progression of Comorbid Depression and Substance Use among Racially Diverse Adults.Journal of prevention (2022) · 2024Article
- Article
- Associations of attention problems and family context in childhood and adolescence with young adult daily smoking: General and smoking-specific family contexts.Drug and alcohol dependence · 2022Article
- Simultaneous use of marijuana and alcohol: Potential prevention targets among young adults who use alcohol.Addictive behaviors · 2022Article
- Intersection of familial risk and environmental social control on high-risk drinking and alcohol dependence in a US national sample of adults.Addictive behaviors · 2021Article
- Neighborhood Structural Factors and Proximal Risk for Youth Substance Use.Prevention science : the official journal of the Society for Prevention Research · 2020Article
- Time-varying effects of family smoking and family management on adolescent daily smoking: The moderating roles of behavioral disinhibition and anxiety.Drug and alcohol dependence · 2019Article
- Neighborhood Poverty Increases Risk for Cigarette Smoking From Age 30 to 39.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2019Article
- General and Specific Predictors of Comorbid Substance Use and Internalizing Problems from Adolescence to Age 33.Prevention science : the official journal of the Society for Prevention Research · 2019Article
- Optimizing Assessment of Risk and Protection for Diverse Adolescent Outcomes: Do Risk and Protective Factors for Delinquency and Substance Use Also Predict Risky Sexual Behavior?Prevention science : the official journal of the Society for Prevention Research · 2019Article
- Neighborhood, Family, and Peer Factors Associated with Early Adolescent Smoking and Alcohol Use.Journal of youth and adolescence · 2018Article
- Nonmedical prescription opioids and pathways of drug involvement in the US: Generational differences.Drug and alcohol dependence · 2018Article
- Psychosocial Factors Related to the Intergenerational Transmission of Externalizing Behaviors in Early Midlife.Substance use & misuse · 2017Article
- A Test-Replicate Approach to Candidate Gene Research on Addiction and Externalizing Disorders: A Collaboration Across Five Longitudinal Studies.Behavior genetics · 2016Article
- Understanding the interplay of individual and social-developmental factors in the progression of substance use and mental health from childhood to adulthood.Development and psychopathology · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDefining phenotypes in studies of tobacco and alcohol misuse is difficult because of the complexity of these behaviors and their strong association with each other and with other problem behaviors. The present paper suggests a strategy for addressing this issue by conceptualizing and partitioning variance in phenotypes into either general or substance/behavior-specific. The paper also applies the general or substance/behavior-specific conceptualization to environmental predictors of tobacco and alcohol misuse and other problem behaviors.
methodsData were drawn from the Seattle Social Development Project, a contemporary, ethnically diverse and gender-balanced longitudinal panel including 808 participants. Latent variable modeling was used to partition variance in young adult (age 24) nicotine dependence, alcohol abuse and dependence, illicit drug abuse and dependence, involvement in crime, and engagement in HIV sexual risk behavior into general problem behavior and behavior-specific variance. Similarly, measures of general, drinking-specific, and smoking-specific adolescent family environment were constructed.
resultsConsistent with expectations, more positive general family environment during adolescence was associated with lower levels of shared variance in problem behaviors at age 24, but not with unique variance in tobacco or alcohol use disorder. Higher levels of family smoking and drinking environments during adolescence, however, were positively associated with unique variance in tobacco and alcohol use disorder, respectively, but did not predict shared variance in problem behaviors.
conclusionsResults support the utility of the proposed approach. Ways in which this approach might contribute to future molecular genetic studies are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.