Evidence map›Paper›PMID 21633930›Full record

ReviewClinical reviews in allergy & immunology2012

Infectious serologies and autoantibodies in hepatitis C and autoimmune disease-associated mixed cryoglobulinemia.

Merav Lidar, Noga Lipschitz, Nancy Agmon-Levin, Pnina Langevitz, Ori Barzilai, Maya Ram, Bat-Sheba Porat-Katz, Nicola Bizzaro, Jan Damoiseaux, Jan Willem Cohen Tervaert and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Epigenetics and Vasculitis: a Comprehensive Review.Clinical reviews in allergy & immunology · 2016
    Review
  2. Diagnostics and treatment of cryoglobulinaemia: it takes two to tango.Clinical reviews in allergy & immunology · 2014
    Review
  3. The challenge of treating orphan disease.Clinical reviews in allergy & immunology · 2014
    Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Merav LidarCenter for Autoimmune Disease, Rheumatology Unit, Sheba Medical Center, Tel Hashomer and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. m-lidar@zahav.net.il
Noga Lipschitz
Nancy Agmon-Levin
Pnina Langevitz
Ori Barzilai
Maya Ram
Bat-Sheba Porat-Katz
Nicola Bizzaro
Jan Damoiseaux
Jan Willem Cohen Tervaert
Salvatore deVita
Stefano Bombardieri
Yehuda Shoenfeld
Maastricht University · NLSheba Medical Center · ILKaplan Medical Center · ILTel Aviv University · ILUniversity of Pisa · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed cryoglobulinemia (MC) syndrome is an immune complex-mediated vasculitis characterized by the clinical triad of purpura, weakness, and arthralgias, the morbidity of which is mainly related to kidney and peripheral nervous system dysfunction as well as to the development of a secondary lymphoma (Ferri et al. Autoimmun Rev 7:114-120, 2007, Lidar et al. Ann N Y Acad Sci 1173:649-657, 2009, Trejo et al. Semin Arthritis Rheum 33:19-28, 2003). MC is associated with infectious and systemic disorders, principally autoimmune and lymphoproliferative diseases. Since the 1990s, a striking association (>90%) between MC and hepatitis C virus (HCV) infection has been established (Ferri and Bombardieri 2004; Pascual et al. J Infect Dis 162:569-570, 1990). However, information regarding the etiopathogenesis of HCV-negative MC is scant (Mascia et al. Dig Liver Dis 39:61-64, 2007). We hereby present our findings, as well as previously published data, regarding the presence of antibodies against infectious agents and autoantibodies in patients with MC in an attempt to establish novel associations which may shed light on the etiopathogenesis of this disease.

Indexed as

AutoantibodiesAutoimmune DiseasesCryoglobulinemiaCryoglobulinsHepacivirusHepatitis CHepatitis C AntibodiesHumansLymphoproliferative DisordersAutoantibodiesCryoglobulinsHepatitis C Antibodies

Identifiers

PMID21633930
OpenAlexW2049516713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.