Evidence map›Paper›PMID 21633929›Full record

ReviewCurrent hypertension reports2011

Potential dopamine-1 receptor stimulation in hypertension management.

Mohammad Asghar, Seyed K Tayebati, Mustafa F Lokhandwala, Tahir Hussain

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Anti-Inflammatory Effects of Peripheral Dopamine.International journal of molecular sciences · 2023
    Review
  2. Role of Dopamine in the Heart in Health and Disease.International journal of molecular sciences · 2023
    Review
  3. Dopamine Receptor DThe Yale journal of biology and medicine · 2023
    Review
  4. Article
  5. Dopamine DHypertension research : official journal of the Japanese Society of Hypertension · 2021
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Activation of angiotensin II type 1 receptors increases DHypertension research : official journal of the Japanese Society of Hypertension · 2017
    Article
  11. Article
  12. Article
  13. Regulation of blood pressure, oxidative stress and AT1R by high salt diet in mutant human dopamine D5 receptor transgenic mice.Hypertension research : official journal of the Japanese Society of Hypertension · 2015
    Article
  14. The renal dopaminergic system: novel diagnostic and therapeutic approaches in hypertension and kidney disease.Translational research : the journal of laboratory and clinical medicine · 2015
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. D5 dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1.Hypertension research : official journal of the Japanese Society of Hypertension · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mohammad AsgharHeart and Kidney Institute, College of Pharmacy, University of Houston, Houston, TX 77204, USA. masghar@uh.edu
Seyed K Tayebati
Mustafa F Lokhandwala
Tahir Hussain
University of Houston · USUniversità di Camerino · IT

Funding

Renal Angiotensin ll Receptor Function in ObesityR01DK061578 · NIDDK · UNIVERSITY OF HOUSTON · PI HUSSAIN, TAHIR · 2003 to 2020
$4.3M
Age-Related Changes in Renal Dopamine Receptor FunctionR01AG025056 · NIA · UNIVERSITY OF HOUSTON · PI LOKHANDWALA, MUSTAFA F. · 2005 to 2009
$1.4M
Exercise and Kidney Dopamine Receptor Function in AgingR03AG029904 · NIA · UNIVERSITY OF HOUSTON · PI ASGHAR, MOHAMMAD · 2008 to 2009
$122k
NIA NIH HHS AG25056NIA NIH HHS AG29904NIDDK NIH HHS DK61578
6 · The paper itself

Abstract

The role of dopamine receptors in blood pressure regulation is well established. Genetic ablation of both dopamine D1-like receptor subtypes (D1, D5) and D2-like receptor subtypes (D2, D3, D4) results in a hypertensive phenotype in mice. This review focuses on the dopamine D1-like receptor subtypes D1 and D5 (especially D1 receptors), as they play a major role in regulating sodium homeostasis and blood pressure. Studies mostly describing the role of renal dopamine D1-like receptors are included, as the kidneys play a pivotal role in the maintenance of sodium homeostasis and the long-term regulation of blood pressure. We also attempt to describe the interaction between D1-like receptors and other proteins, especially angiotensin II type 1 and type 2 receptors, which are involved in the maintenance of sodium homeostasis and blood pressure. Finally, we discuss a new concept of renal D1 receptor regulation in hypertension that involves oxidative stress mechanisms.

Indexed as

Blood PressureG-Protein-Coupled Receptor KinasesHomeostasisHumansHypertensionOxidative StressReceptor, Angiotensin, Type 1Receptor, Angiotensin, Type 2Receptors, Dopamine D1G-Protein-Coupled Receptor KinasesReceptor, Angiotensin, Type 1Receptor, Angiotensin, Type 2Receptors, Dopamine D1

Identifiers

PMID21633929
OpenAlexW2046942736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.