ArticleKidney international2011
Elevated depressive affect is associated with adverse cardiovascular outcomes among African Americans with chronic kidney disease.
Article in Kidney international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 51 citations in OpenAlex.
- Effects of acceptance of disability on death or dialysis in chronic kidney disease patients: a 3-year prospective cohort study.BMC nephrology · 2015Trial
- Dose-dependent association of depression with incidence of end-stage kidney disease and all-cause mortality, CKD-JAC study: a retrospective cohort study.Clinical and experimental nephrology · 2026Article
- Cardiorenal Syndrome and Depressive Symptoms: Exploring the Mood-Kidney Link With Heart Failure Risk in a Post-hoc Analysis of SPRINT.Kidney medicine · 2026Article
- Relationship of Depression With Incident Cardiovascular Disease in Individuals With Chronic Kidney Disease.Circulation reports · 2026Article
- The trajectory of frailty index and its association with rapid decline in kidney function and the incidence of chronic kidney disease: evidence from the China health and retirement longitudinal study.Aging clinical and experimental research · 2025Article
- Article
- Cost-Effectiveness of Empagliflozin in CKD with or without Albuminuria.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- A retrospective cohort study on the bidirectional association between depression and chronic kidney disease.Frontiers in nephrology · 2025Article
- Roles of Parathyroid Hormone and Fibroblast Growth Factor 23 in Advanced Chronic Kidney Disease.Endocrinology and metabolism (Seoul, Korea) · 2024Review
- Depressive Symptoms, Antidepressants, and Clinical Outcomes in Chronic Kidney Disease: Findings from the CRIC Study.Kidney medicine · 2024Article
- Association between incident depression and clinical outcomes in patients with chronic kidney disease.Clinical kidney journal · 2023Article
- Depression and incident cardiovascular disease among patients with chronic kidney disease.International journal of cardiology. Cardiovascular risk and prevention · 2023Article
- Persistent Depressive Symptoms and the Changes in Serum Cystatin C Levels in the Elderly: A Longitudinal Cohort Study.Frontiers in psychiatry · 2022Article
- Religious Service Attendance and Mortality among Adults in the United States with Chronic Kidney Disease.International journal of environmental research and public health · 2021Article
- Low High-Sensitivity C-Reactive Protein Level in Korean Patients With Chronic Kidney Disease and Its Predictive Significance for Cardiovascular Events, Mortality, and Adverse Kidney Outcomes: Results From KNOW-CKD.Journal of the American Heart Association · 2020Article
- Association Between Serum Uric Acid and Depression in Patients with Chronic Kidney Disease not Requiring Kidney Dialysis: Cross-Sectional and Longitudinal Analyses.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Dietary Patterns and Health Outcomes among African American Maintenance Hemodialysis Patients.Nutrients · 2020Article
- Expressions of Gratitude and Positive Emotion among Hemodialysis Patients: Qualitative Findings.The journal of nephrology social work · 2020Article
- Association between health related quality of life and progression of chronic kidney disease.Scientific reports · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 11 institutions in 1 country.
Funding
Abstract
This study was designed to examine the impact of elevated depressive affect on health outcomes among participants with hypertensive chronic kidney disease in the African-American Study of Kidney Disease and Hypertension (AASK) Cohort Study. Elevated depressive affect was defined by Beck Depression Inventory II (BDI-II) thresholds of 11 or more, above 14, and by 5-Unit increments in the score. Cox regression analyses were used to relate cardiovascular death/hospitalization, doubling of serum creatinine/end-stage renal disease, overall hospitalization, and all-cause death to depressive affect evaluated at baseline, the most recent annual visit (time-varying), or average from baseline to the most recent visit (cumulative). Among 628 participants at baseline, 42% had BDI-II scores of 11 or more and 26% had a score above 14. During a 5-year follow-up, the cumulative incidence of cardiovascular death/hospitalization was significantly greater for participants with baseline BDI-II scores of 11 or more compared with those with scores <11. The baseline, time-varying, and cumulative elevated depressive affect were each associated with a significant higher risk of cardiovascular death/hospitalization, especially with a time-varying BDI-II score over 14 (adjusted HR 1.63) but not with the other outcomes. Thus, elevated depressive affect is associated with unfavorable cardiovascular outcomes in African Americans with hypertensive chronic kidney disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.