Evidence map›Paper›PMID 21633380›Full record

ReviewNature reviews. Neuroscience2011

Cognitive and neurobiological mechanisms of alcohol-related aggression.

Adrienne J Heinz, Anne Beck, Andreas Meyer-Lindenberg, Philipp Sterzer, Andreas Heinz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  4. Imaging resilience and recovery in alcohol dependence.Addiction (Abingdon, England) · 2018
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63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adrienne J HeinzDepartment of Psychology, University of Illinois at Chicago, 1007 W Harrison Street, MC 285 Chicago, Illinois 60607, USA. andreas.heinz@ charite.de
Anne Beck
Andreas Meyer-Lindenberg
Philipp Sterzer
Andreas Heinz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol-related violence is a serious and common social problem. Moreover, violent behaviour is much more common in alcohol-dependent individuals. Animal experiments and human studies have provided insights into the acute effect of alcohol on aggressive behaviour and into common factors underlying acute and chronic alcohol intake and aggression. These studies have shown that environmental factors, such as early-life stress, interact with genetic variations in serotonin-related genes that affect serotonergic and GABAergic neurotransmission. This leads to increased amygdala activity and impaired prefrontal function that, together, predispose to both increased alcohol intake and impulsive aggression. In addition, acute and chronic alcohol intake can further impair executive control and thereby facilitate aggressive behaviour.

Indexed as

NeurobiologyAggressionAlcohol DrinkingAnimalsBrainCentral Nervous System DepressantsCognition DisordersDisease Models, AnimalEthanolHumansIndividualityModels, NeurologicalReceptors, NeurotransmitterSocial BehaviorTime FactorsCentral Nervous System DepressantsEthanolReceptors, Neurotransmitter

Identifiers

PMID21633380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.