Evidence map›Paper›PMID 21633188›Full record

ArticlePlant signaling & behavior2011

Dual roles for FY in the regulation of FLC.

Wei Feng, Scott D Michaels

Abstract read
In one paragraph

Article in Plant signaling & behavior, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Genetics of days to flowering, maturity and plant height in natural and derived forms of Brassica rapa L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021
    Article
  5. Article
  6. Overexpression of blueberryHorticulture research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wei FengDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Scott D Michaels

Funding

Molecular analysis of the autonomous pathwayR01GM075060 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI MICHAELS, SCOTT · 2007 to 2016
$2.8M
NIGMS NIH HHS 1R01GM075060NIGMS NIH HHS R01 GM075060
6 · The paper itself

Abstract

In Arabidopsis, the flowering decision is determined by multiple pathways that integrate information from both endogenous signals and environmental cues. The genes of the autonomous pathway promote flowering by suppressing the expression of the floral repressor FLOWERING LOCUS C (FLC). Thus, autonomous-pathway mutants have elevated levels of FLC and are late flowering. Previous work has shown that two autonomous pathway proteins, FCA and FY, physically interact and this interaction is important in the repression of FLC. Recent work from our laboratory has shown that a hypomorphic allele of FY (fy-5) can cause earlier or later flowering, depending on the genetic background. These results suggest that FY has the potential to act as both an activator and a repressor of FLC. The FLC-activating activity of FY appears to be FCA-independent, as fy-5 causes earlier flowering in an fca-null background. Here we present a speculative model that reconciles these opposing phenotypes by proposing a dual role for FY in the regulation of flowering time.

Indexed as

ArabidopsisArabidopsis ProteinsMADS Domain ProteinsModels, BiologicalmRNA Cleavage and Polyadenylation FactorsArabidopsis ProteinsAt5g10140 protein, ArabidopsisFY protein, ArabidopsisMADS Domain ProteinsmRNA Cleavage and Polyadenylation Factors

Identifiers

PMID21633188
PMCPMC3172842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.