Evidence map›Paper›PMID 21632906›Full record

ReviewCleveland Clinic journal of medicine2011

Immune thrombocytopenia: no longer 'idiopathic'.

Keith McCrae

Open access · bronzeAbstract readReview
In one paragraph

Review in Cleveland Clinic journal of medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 94 citations in OpenAlex.

  1. Trial
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  15. Pharmacokinetics, Pharmacodynamics, Efficacy and Safety of a Romiplostim Biosimilar in Chronic Refractory Immune Thrombocytopenic Purpura (ITP) Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Corticosteroid overuse in adults with immune thrombocytopenia: Cause for concern.Research and practice in thrombosis and haemostasis · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Keith McCraeDepartment of Hematologic Oncology and Blood Disorders, Taussig CancerInstitute, Cleveland Clinic, Cleveland, OH 44195, USA. mccraek@ccf.org
Cleveland Clinic Lerner College of Medicine · US

Funding

Transfusion Medicine/Hemostasis Clinical Research NetworkU01HL072033 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI MCCRAE, KEITH R. · 2002 to 2012
$1.7M
NHLBI NIH HHS U01 HL072033
6 · The paper itself

Abstract

Immune thrombocytopenia (ITP) is a common hematologic disorder. Its pathogenesis involves both accelerated platelet destruction and impaired platelet production. First-line agents are usually effective initially but do not provide long-term responses. Splenectomy remains an effective long-term therapy, as does rituximab (Rituxan) in a subset of patients. Thrombopoietic agents offer a new alternative, although their place in the overall management of ITP remains uncertain.

Indexed as

Adrenal Cortex HormonesAntibodies, Monoclonal, Murine-DerivedAnti-Inflammatory AgentsHumansImmunologic FactorsPurpura, Thrombocytopenic, IdiopathicReceptors, ThrombopoietinRituximabSplenectomyAdrenal Cortex HormonesAntibodies, Monoclonal, Murine-DerivedAnti-Inflammatory AgentsImmunologic FactorsReceptors, ThrombopoietinRituximab

Identifiers

PMID21632906
PMCPMC3410635
OpenAlexW1970837685

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.