Evidence map›Paper›PMID 21632770›Full record

ArticleJournal of virology2011

Shared ancestry between a newfound mole-borne hantavirus and hantaviruses harbored by cricetid rodents.

Hae Ji Kang, Shannon N Bennett, Andrew G Hope, Joseph A Cook, Richard Yanagihara

Abstract read
In one paragraph

Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Orthohantaviruses, Emerging Zoonotic Pathogens.Pathogens (Basel, Switzerland) · 2020
    Review
  7. Review
  8. Article
  9. Article
  10. Genetic Diversity and Phylogeography ofFrontiers in cellular and infection microbiology · 2020
    Article
  11. Viruses · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hae Ji KangDepartment of Pediatrics and Tropical Medicine, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii 96813, USA.
Shannon N Bennett
Andrew G Hope
Joseph A Cook
Richard Yanagihara
University of Hawaiʻi at Mānoa · USUniversity of New Mexico · US

Funding

Vaccines and Diagnostics TrialsU54AI065359 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARBOUR, ALAN G. · 2005 to 2013
$88.8M
WORLDWIDE EPIDEMIOLOGY &EPIZOOTIOLOGY OF HANTAVIRUSG12RR003061 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI OSTRANDER, GARY K · 1986 to 2011
$32.3M
UHI COBRE: P3: GROUP A STREPT IN RELATION TO ACUTE RHEUMATIC FEVER IN HAWAIIP20RR018727 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI HOANG, TUNG T · 2003 to 2011
$13.8M
Intraspecies Transmission and Infectivity of Insectivore-Borne HantavirusesR01AI075057 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI YANAGIHARA, RICHARD · 2008 to 2011
$1.5M
NCRR NIH HHS G12 RR003061NCRR NIH HHS G12RR003061NCRR NIH HHS P20 RR018727NCRR NIH HHS P20RR018727NIAID NIH HHS R01 AI075057NIAID NIH HHS R01AI075057NIAID NIH HHS U54 AI065359NIAID NIH HHS U54AI065359
6 · The paper itself

Abstract

Discovery of genetically distinct hantaviruses in multiple species of shrews (order Soricomorpha, family Soricidae) and moles (family Talpidae) contests the conventional view that rodents (order Rodentia, families Muridae and Cricetidae) are the principal reservoir hosts and suggests that the evolutionary history of hantaviruses is far more complex than previously hypothesized. We now report on Rockport virus (RKPV), a hantavirus identified in archival tissues of the eastern mole (Scalopus aquaticus) collected in Rockport, TX, in 1986. Pairwise comparison of the full-length S, M, and L genomic segments indicated moderately low sequence similarity between RKPV and other soricomorph-borne hantaviruses. Phylogenetic analyses, using maximum-likelihood and Bayesian methods, showed that RKPV shared a most recent common ancestor with cricetid-rodent-borne hantaviruses. Distributed widely across the eastern United States, the fossorial eastern mole is sympatric and syntopic with cricetid rodents known to harbor hantaviruses, raising the possibility of host-switching events in the distant past. Our findings warrant more-detailed investigations on the dynamics of spillover and cross-species transmission of present-day hantaviruses within communities of rodents and moles.

Indexed as

AnimalsArvicolinaeBase SequenceDisease ReservoirsDNA, MitochondrialDNA PrimersMolesOrthohantavirusPhylogenyReverse Transcriptase Polymerase Chain ReactionTexasDNA, MitochondrialDNA Primers

Identifiers

PMID21632770
PMCPMC3147906
OpenAlexW2022001300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.