ReviewThe Journal of biological chemistry2011
New applications of mass spectrometry in lipid analysis.
Review in The Journal of biological chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 58 citations in OpenAlex.
- High Throughput LC-MS Platform for Large Scale Screening of Bioactive Polar Lipids in Human Plasma and Serum.Journal of proteome research · 2022Article
- Lipidomics in Biomarker Research.Handbook of experimental pharmacology · 2022Review
- Targeted Lipidomics of Drosophila melanogaster During Development.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Mass Spectrometry-Based Lipidomics: An Overview.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Surface-Enhanced Raman Spectroscopy Characterization of Breast Cell Phenotypes: Effect of Nanoparticle Geometry.ACS applied nano materials · 2019Article
- "Redox lipidomics technology: Looking for a needle in a haystack".Chemistry and physics of lipids · 2019Review
- Half a Century of Research on Membrane-Containing Bacteriophages: Bringing New Concepts to Modern Virology.Viruses · 2019Review
- Article
- Mass spectrometry-based shotgun lipidomics - a critical review from the technical point of view.Analytical and bioanalytical chemistry · 2018Review
- Review
- Extraction, chromatographic and mass spectrometric methods for lipid analysis.Biomedical chromatography : BMC · 2016Review
- Differential sensing for the regio- and stereoselective identification and quantitation of glycerides.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification.Analytical chemistry · 2015Article
- Structural characterization of gangliosides and glycolipids via ultraviolet photodissociation mass spectrometry.Analytical chemistry · 2013Article
- Quantitative profiling of major neutral lipid classes in human meibum by direct infusion electrospray ionization mass spectrometry.Investigative ophthalmology & visual science · 2013Article
- Mammalian fatty acid synthase activity from crude tissue lysates tracing ¹³C-labeled substrates using gas chromatography-mass spectrometry.Analytical biochemistry · 2012Article
- Mass spectrometric identification of phospholipids in human tears and tear lipocalin.Investigative ophthalmology & visual science · 2012Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Mass spectrometry has emerged as a powerful tool for the analysis of all lipids. Lipidomic analysis of biological systems using various approaches is now possible with a quantitative measurement of hundreds of lipid molecular species. Although availability of reference and internal standards lags behind the field, approaches using stable isotope-labeled derivative tagging permit precise determination of specific phospholipids in an experimental series. The use of reactivity of ozone has enabled assessment of double bond positions in fatty acyl groups even when species remain in complex lipid mixtures. Rapid scanning tandem mass spectrometers are capable of quantitative analysis of hundreds of targeted lipids at high sensitivity in a single on-line chromatographic separation. Imaging mass spectrometry of lipids in tissues has opened new insights into the distribution of lipid molecular species with promising application to study pathophysiological events and diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.