ReviewResults and problems in cell differentiation2011
Function of the A-type cyclins during gametogenesis and early embryogenesis.
Review in Results and problems in cell differentiation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- The Anaphase Promoting Complex/Cyclosome Subunit 11 and Its Role in Organ Size and Plant Development.Frontiers in plant science · 2021Article
- Article
- Loss ofFrontiers in cell and developmental biology · 2021Article
- Cancer testis antigen Cyclin A1 harbors several HLA-A*02:01-restricted T cell epitopes, which are presented and recognized in vivo.Cancer immunology, immunotherapy : CII · 2020Article
- Comparative transcriptome analysis digs out genes related to antifreeze between fresh and frozen-thawed rooster sperm.Poultry science · 2020Article
- Minor zygotic gene activation is essential for mouse preimplantation development.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Preterm labor in the absence of acute histologic chorioamnionitis is characterized by cellular senescence of the chorioamniotic membranes.American journal of obstetrics and gynecology · 2017Article
- Cyclin A2 modulates kinetochore-microtubule attachment in meiosis II.The Journal of cell biology · 2017Article
- Comparison of gene expression response to neutron and x-ray irradiation using mouse blood.BMC genomics · 2017Article
- Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy.Nature reviews. Cancer · 2014Review
- Role of cyclins in controlling progression of mammalian spermatogenesis.The International journal of developmental biology · 2013Review
- The R2R3 MYB transcription factors FOUR LIPS and MYB88 regulate female reproductive development.Journal of experimental botany · 2012Article
- The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer.Cell cycle (Georgetown, Tex.) · 2012Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
The cyclins and their cyclin-dependent kinase partners, the Cdks, are the basic components of the machinery that regulates the passage of cells through the cell cycle. Among the cyclins, those known as the A-type cyclins are unique in that in somatic cells, they appear to function at two stages of the cell cycle, at the G1-S transition and again as the cells prepare to enter M-phase. Higher vertebrate organisms have two A-type cyclins, cyclin A1 and cyclin A2, both of which are expressed in the germ line and/or early embryo, following highly specialized patterns that suggest functions in both mitosis and meiosis. Insight into their in vivo functions has been obtained from gene targeting experiments in the mouse model. Loss of cyclin A1 results in disruption of spermatogenesis and male sterility due to cell arrest in the late diplotene stage of the meiotic cell cycle. In contrast, cyclin A2-deficiency is marked by early embryonic lethality; thus, understanding the function of cyclin A2 in the adult germ line awaits conditional mutagenesis or other approaches to knock down its expression.
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