ArticleIndian journal of pediatrics2011
Characteristics of pediatric scrub typhus during an outbreak in the North Eastern region of India: peculiarities in clinical presentation, laboratory findings and complications.
Article in Indian journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spatiotemporal epidemiology and clinical manifestations of two decades of scrub typhus in India: a systematic review and meta-analysis.BMJ global health · 2025Pooled it
- Article
- Frequency and distribution of eschar in patients with scrub typhus in India: systematic review of literature and meta-analysis.Le infezioni in medicina · 2024Review
- Scrub Typhus in Children: A Prospective Observational Study in a Tertiary Care Hospital in Eastern India.Cureus · 2023Article
- Clinical profile and outcomes of pediatric scrub typhus associated with elevated hepatic transaminases.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Article
- Scrub Typhus in Paediatric Age Group at a Tertiary Care Centre of Eastern India: Clinical, Biochemical Profile and Complications.Journal of family medicine and primary care · 2022Article
- Article
- Genotypic Characterization ofFrontiers in microbiology · 2022Article
- Diagnosis of scrub typhus: recent advancements and challenges.3 Biotech · 2020Review
- Prevalence of scrub typhus in a tertiary care centre in Telangana, south India.Iranian journal of microbiology · 2020Article
- Scrub typhus strikes back: Are we ready?Medical journal, Armed Forces India · 2019Review
- Predictors of Severity in Pediatric Scrub Typhus.Indian journal of pediatrics · 2018Observational
- Meningitis due to scrub typhus: the importance of a differential diagnosis in an endemic area.BMJ case reports · 2018Article
- A Review of Scrub Typhus (Orientia tsutsugamushi and Related Organisms): Then, Now, and Tomorrow.Tropical medicine and infectious disease · 2018Review
- A review of the global epidemiology of scrub typhus.PLoS neglected tropical diseases · 2017Review
- Acute undifferentiated fever in India: a multicentre study of aetiology and diagnostic accuracy.BMC infectious diseases · 2017Article
- Clinico - Laboratory Profile of Scrub Typhus - An Emerging Rickettsiosis in India.Indian journal of pediatrics · 2016Article
- Severe scrub typhus infection: Clinical features, diagnostic challenges and management.World journal of critical care medicine · 2015Review
- Evidence for a specific host-endosymbiont relationship between 'Rickettsia sp. genotype RF2125' and Ctenocephalides felis orientis infesting dogs in India.Parasites & vectors · 2015Article
- Molecular epidemiology and genetic diversity of Orientia tsutsugamushi from patients with scrub typhus in 3 regions of India.Emerging infectious diseases · 2015Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify and report a recent outbreak of scrub typhus cases recorded from October 2009 to January 2010 in the state of Meghalaya, India.
methodsThe case sheets of all the children were retrieved and reviewed retrospectively. Twenty four (24) patients, who were both clinically and serologically confirmed as scrub typhus cases were included in the study.
resultsFever for more than 1 wk duration was the most common manifestation (100%) followed by splenomegaly (45.8%), eschar (41.7%), cough (37.5%), hepatomegaly (33.3%), headache and body ache (25%), pain abdomen (25%), vomiting (20.8%), altered sensorium (16.6%), seizures (12.5%) lymphadenopathy (12.5%), and loose stools (8.3%). Meningoencephalitis was the most common complication (29.2%) followed by pneumonia (16.3%) and subconjunctival hemorrhage (8.3%).Cortical blindness, septic shock, peritonitis, myocarditis with CCF, pancytopenia, acute renal failure, coagulopathy, prolonged oxygen dependency and urinary tract infection (UTI) were found in one of each case. Hyponatremia (66.7%), elevated liver enzymes without significant rise of bilirubin (58.3%), hypoalbuminemia (52.2%) and thrombocytopenia (26%) were the other significant laboratory findings. Patients were treated with chloramphenicol, doxycycline and azithromycin. There was no mortality.
conclusionsThis is the first outbreak report from the north eastern region of India with varied clinical presentations, laboratory investigations and complications. Weil Felix test still remains fruitful for diagnosing this disease in a resource limited set up.
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