ArticleExtremophiles : life under extreme conditions2011
Regulation of expression of trehalose-6-phosphate synthase during cold shock in Arthrobacter strain A3.
Article in Extremophiles : life under extreme conditions, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Subzero cell division, respiration, and genomic traits of cryophilicFrontiers in microbiology · 2025Article
- Linking genomic and physiological characteristics of psychrophilic Arthrobacter to metagenomic data to explain global environmental distribution.Microbiome · 2021Article
- A trehalose biosynthetic enzyme doubles as an osmotic stress sensor to regulate bacterial morphogenesis.PLoS genetics · 2017Article
- Genomic and phenotypic insights into the ecology of Arthrobacter from Antarctic soils.BMC genomics · 2015Article
- Bacterial composition of soils of the Lake Wellman area, Darwin Mountains, Antarctica.Extremophiles : life under extreme conditions · 2013Article
- Genome Sequence of Streptomyces violaceusniger Strain SPC6, a Halotolerant Streptomycete That Exhibits Rapid Growth and Development.Genome announcements · 2013Article
- Cloning, expression and characterization of trehalose-6-phosphate phosphatase from a psychrotrophic bacterium, Arthrobacter strain A3.World journal of microbiology & biotechnology · 2012Article
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13 authors.
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Abstract
Trehalose is a chemical chaperone known to protect a variety of organisms against cold stress. Members of the genus Arthrobacter, which belongs to the Actinomycetales group, exhibit strong resistance to stress conditions, but exactly how trehalose synthesis is regulated in conditions of cold stress is still unknown. Here, we report that Arthrobacter strain A3, which was isolated from the alpine permafrost, has only two trehalose synthesis pathways (OtsA/B and TreS), while other Arthrobacter spp. have three. Mutants and immunoblot analyses indicate that trehalose is mainly synthesized via OtsA at low temperatures in Arthrobacter strain A3. Therefore, we have focused on the regulation of OtsA expression during cold shock. The results indicated that both low temperature and accumulation of trehalose can inhibit OtsA expression. The elongation factor Tu, which binds to OtsA, stabilizes the expression of OtsA in the cold.
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