ArticlePlant physiology2011
Perturbation of spermine synthase gene expression and transcript profiling provide new insights on the role of the tetraamine spermine in Arabidopsis defense against Pseudomonas viridiflava.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 109 citations in OpenAlex.
- Blooming resilience: transcriptomic insights into cotton flower responses to boll weevil infestation.Plant cell reports · 2025Article
- Plant regeneration capacity in seeds of three species of Miconia (Melastomataceae) may be related to endogenous polyamine profiles.Protoplasma · 2024Article
- NMR and LC-MS-based metabolomics to investigate the efficacy of a commercial bio stimulant for the treatment of wheat (Triticum aestivum).Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Genome-wide identification of polyamine metabolism and ethylene synthesis genes in Chenopodium quinoa Willd. and their responses to low-temperature stress.BMC genomics · 2024Article
- Piriformospora indica recruits host-derived putrescine for growth promotion in plants.Plant physiology · 2022Article
- Mitogen-Activated Protein Kinase 4-Regulated Metabolic Networks.International journal of molecular sciences · 2022Article
- Genome-Wide Identification and Functional Analysis of Polyamine Oxidase Genes in Maize Reveal Essential Roles in Abiotic Stress Tolerance.Frontiers in plant science · 2022Article
- Putrescine Depletion Affects Arabidopsis Root Meristem Size by Modulating Auxin and Cytokinin Signaling and ROS Accumulation.International journal of molecular sciences · 2021Article
- Review
- Article
- Metabolism and Regulatory Functions ofFrontiers in plant science · 2021Review
- Arbuscular Mycorrhiza-Mediated Regulation of Polyamines and Aquaporins During Abiotic Stress: Deep Insights on the Recondite Players.Frontiers in plant science · 2021Review
- Polyamine-Induced Hormonal Changes inInternational journal of molecular sciences · 2019Article
- A novel hydroxycinnamoyl transferase for synthesis of hydroxycinnamoyl spermine conjugates in plants.BMC plant biology · 2019Article
- Spermine Differentially Refines Plant Defense Responses Against Biotic and Abiotic Stresses.Frontiers in plant science · 2019Review
- Polyamines and Legumes: Joint Stories of Stress, Nitrogen Fixation and Environment.Frontiers in plant science · 2019Review
- Spermine Confers Stress Resilience by Modulating Abscisic Acid Biosynthesis and Stress Responses in Arabidopsis Plants.Frontiers in plant science · 2019Article
- The Polyamine Putrescine Contributes to HFrontiers in plant science · 2019Article
- Transcriptional Modulation of Polyamine Metabolism in Fruit Species Under Abiotic and Biotic Stress.Frontiers in plant science · 2019Review
- Conservation of Thermospermine Synthase Activity in Vascular and Non-vascular Plants.Frontiers in plant science · 2019Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of the tetraamine spermine in plant defense against pathogens was investigated by using the Arabidopsis (Arabidopsis thaliana)-Pseudomonas viridiflava pathosystem. The effects of perturbations of plant spermine levels on susceptibility to bacterial infection were evaluated in transgenic plants (35S::spermine synthase [SPMS]) that overexpressed the SPMS gene and accumulated spermine, as well as in spms mutants with low spermine levels. The former exhibited higher resistance to P. viridiflava than wild-type plants, while the latter were more susceptible. Exogenous supply of spermine to wild-type plants also increased disease resistance. Increased resistance provided by spermine was partly counteracted by the polyamine oxidase inhibitor SL-11061, demonstrating that the protective effect of spermine partly depends on its oxidation. In addition, global changes in gene expression resulting from perturbations of spermine levels were analyzed by transcript profiling 35S::SPMS-9 and spms-2 plants. Overexpression of 602 genes was detected in 35S::SPMS-9 plants, while 312 genes were down-regulated, as compared to the wild type. In the spms-2 line, 211 and 158 genes were up- and down-regulated, respectively. Analysis of gene ontology term enrichment demonstrated that many genes overexpressed only in 35S::SPMS-9 participate in pathogen perception and defense responses. Notably, several families of disease resistance genes, transcription factors, kinases, and nucleotide- and DNA/RNA-binding proteins were overexpressed in this line. Thus, a number of spermine-responsive genes potentially involved in resistance to P. viridiflava were identified. The obtained results support the idea that spermine contributes to plant resistance to P. viridiflava.
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