ArticlePlant physiology2011
CAST AWAY, a membrane-associated receptor-like kinase, inhibits organ abscission in Arabidopsis.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- Primary nitrate responses mediated by calcium signalling and diverse protein phosphorylation.Journal of experimental botany · 2020Pooled it
- The RhMPK3-RhLOB41-RhWRKY9 module orchestrates ethylene-induced petal abscission via dual control of ROS homeostasis in rose.Science advances · 2026Article
- The HAESA family of receptor-like kinases: abscission pathways and emerging functions.Frontiers in plant science · 2026Review
- Abscission zones: cellular interfaces for the programmed separation of organs.Annals of botany · 2025Review
- Abscission in plants: from mechanism to applications.Advanced biotechnology · 2024Review
- Receptor-like cytoplasmic kinases of different subfamilies differentially regulate SOBIR1/BAK1-mediated immune responses in Nicotiana benthamiana.Nature communications · 2024Article
- Dissection of the IDA promoter identifies WRKY transcription factors as abscission regulators in Arabidopsis.Journal of experimental botany · 2024Article
- Identification of QTLs involved in destemming and fruit quality for mechanical harvesting of New Mexico pod-type green chile.Frontiers in plant science · 2024Article
- The rose INFLORESCENCE DEFICIENT IN ABSCISSION-LIKE genes, RbIDL1 and RbIDL4, regulate abscission in an ethylene-responsive manner.Plant cell reports · 2023Article
- Advances in Rice Seed Shattering.International journal of molecular sciences · 2023Review
- Genetics of destemming in pepper: A step towards mechanical harvesting.Frontiers in genetics · 2023Article
- A novel sugar beet cyst nematode effector 2D01 targets the Arabidopsis HAESA receptor-like kinase.Molecular plant pathology · 2022Article
- Receptor-like cytoplasmic kinases PBL34/35/36 are required for CLE peptide-mediated signaling to maintain shoot apical meristem and root apical meristem homeostasis in Arabidopsis.The Plant cell · 2022Article
- Article
- Receptor-like protein kinases in plant reproduction: Current understanding and future perspectives.Plant communications · 2022Review
- Proteomics approach to investigating osmotic stress effects on pistachio.Frontiers in plant science · 2022Article
- Multi-scale comparative transcriptome analysis reveals key genes and metabolic reprogramming processes associated with oil palm fruit abscission.BMC plant biology · 2021Article
- Plant plasma membrane-resident receptors: Surveillance for infections and coordination for growth and development.Journal of integrative plant biology · 2021Review
- Physiological, Biochemical, and Transcriptomic Responses ofInternational journal of molecular sciences · 2020Article
- Receptor-Like Protein Kinases Function Upstream of MAPKs in Regulating Plant Development.International journal of molecular sciences · 2020Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Receptor-like kinase-mediated cell signaling pathways play fundamental roles in many aspects of plant growth and development. A pair of Arabidopsis (Arabidopsis thaliana) leucine-rich repeat receptor-like kinases (LRR-RLKs), HAESA (HAE) and HAESA-LIKE2 (HSL2), have been shown to activate the cell separation process that leads to organ abscission. Another pair of LRR-RLKs, EVERSHED (EVR) and SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1, act as inhibitors of abscission, potentially by modulating HAE/HSL2 activity. Cycling of these RLKs to and from the cell surface may be regulated by NEVERSHED (NEV), a membrane trafficking regulator that is essential for organ abscission. We report here the characterization of CAST AWAY (CST), a receptor-like cytoplasmic kinase that acts as a spatial inhibitor of cell separation. Disruption of CST suppresses the abscission defects of nev mutant flowers and restores the discrete identity of the trans-Golgi network in nev abscission zones. After organ shedding, enlarged abscission zones with obscured boundaries are found in nev cst flowers. We show that CST is a dual-specificity kinase in vitro and that myristoylation at its amino terminus promotes association with the plasma membrane. Using the bimolecular fluorescence complementation assay, we have detected interactions of CST with HAE and EVR at the plasma membrane of Arabidopsis protoplasts and hypothesize that CST negatively regulates cell separation signaling directly and indirectly. A model integrating the potential roles of receptor-like kinase signaling and membrane trafficking during organ separation is presented.
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