ArticleAntimicrobial agents and chemotherapy2011
Genetic context and structural diversity of class 1 integrons from human commensal bacteria in a hospital intensive care unit.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Prevalence and molecular characterization of multi-resistantAnimal biotechnology · 2024Article
- Genetic Relationship betweenAnimals : an open access journal from MDPI · 2022Article
- Detection of Acquired Antibiotic Resistance Genes in Domestic Pig (Antibiotics (Basel, Switzerland) · 2022Article
- Nosocomial Infections with IMP-19-Producing Pseudomonas aeruginosa Linked to Contaminated Sinks, France.Emerging infectious diseases · 2017Article
- Occurrences and Characterization of Antibiotic-Resistant Bacteria and Genetic Determinants of Hospital Wastewater in a Tropical Country.Antimicrobial agents and chemotherapy · 2016Article
- Species Diversity of Environmental GIM-1-Producing Bacteria Collected during a Long-Term Outbreak.Applied and environmental microbiology · 2016Article
- Class 1 Integrons and the Antiseptic Resistance Gene (qacEΔ1) in Municipal and Swine Slaughterhouse Wastewater Treatment Plants and Wastewater-Associated Methicillin-Resistant Staphylococcus aureus.International journal of environmental research and public health · 2015Article
- Prevalence of Class 1 Integrons and Extended Spectrum Beta Lactamases among Multi-Drug Resistant Escherichia coli Isolates from North of Iran.Iranian biomedical journal · 2015Article
- Integrons: past, present, and future.Microbiology and molecular biology reviews : MMBR · 2014Review
- Antimicrobial resistance determinants in Acinetobacter baumannii isolates taken from military treatment facilities.Antimicrobial agents and chemotherapy · 2014Article
- Molecular characterization of class 1 integrons and gene cassettes in multidrug resistant (MDR) Klebsiella spp. isolated from hospitalized and outpatients in Iran, 2009.Iranian journal of microbiology · 2013Article
- Widespread dissemination of class 1 integron components in soils and related ecosystems as revealed by cultivation-independent analysis.Frontiers in microbiology · 2013Article
- Article
- Mobile elements, zoonotic pathogens and commensal bacteria: conduits for the delivery of resistance genes into humans, production animals and soil microbiota.Frontiers in microbiology · 2013Article
- Integron involvement in environmental spread of antibiotic resistance.Frontiers in microbiology · 2012Article
- A trade-off between the fitness cost of functional integrases and long-term stability of integrons.PLoS pathogens · 2012Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Most surveys for class 1 integrons are at least partly predicated on PCR screening that targets integron conserved regions. However, class 1 integrons are structurally diverse, so dependence on conserved regions may lead to missing clinically relevant examples of class 1 integrons. Here, we surveyed a commensal population of bacteria from patients in an intensive care unit to identify class 1 integrons irrespective of their structure or genetic context. We identified several examples of class 1 integrons linked to complete Tn402-like or Tn402 hybrid transposition modules and diverse insertion points with respect to the inverted repeat IRi boundary. The diversity and abundance of class 1 integrons identified are such that many novel elements seen here would not have been identified by commonly used methods, and they revealed an additional level of complexity.
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