ArticleBMC evolutionary biology2011
The 5S rDNA family evolves through concerted and birth-and-death evolution in fish genomes: an example from freshwater stingrays.
Article in BMC evolutionary biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 76 citations in OpenAlex.
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- Could Horizontal Gene Transfer Explain 5S rDNA Similarities Between Frogs and Worm Parasites?Biomolecules · 2025Article
- Does time matter? Intraspecific diversity of ribosomal RNA genes in lineages of the allopolyploid model grass Brachypodium hybridum with different evolutionary ages.BMC plant biology · 2024Article
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- The Dynamic Interplay Between Ribosomal DNA and Transposable Elements: A Perspective From Genomics and Cytogenetics.Molecular biology and evolution · 2024Article
- Intragenomic rDNA variation - the product of concerted evolution, mutation, or something in between?Heredity · 2023Review
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- 5S Ribosomal DNA of GenusFrontiers in plant science · 2022Article
- Organization and expression analysis of 5S and 45S ribosomal DNA clusters in autotetraploid Carassius auratus.BMC ecology and evolution · 2021Article
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- Characterizing the ribosomal tandem repeat and its utility as a DNA barcode in lichen-forming fungi.BMC evolutionary biology · 2020Article
- Molecular Organization and Chromosomal Localization Analysis ofFrontiers in genetics · 2019Article
- Sequence characterization of the 5S ribosomal DNA and the internal transcribed spacer (ITS) region in four European Donax species (Bivalvia: Donacidae).BMC genetics · 2018Article
- Evolutionary Dynamics of Copy Number and Meiotic Recombination in Murine 5S rDNA: Possible Involvement of Natural Selection.Journal of molecular evolution · 2018Article
- Variations in 5S rDNAs in diploid and tetraploid offspring of red crucian carp × common carp.BMC genetics · 2017Article
- Higher-order organisation of extremely amplified, potentially functional and massively methylated 5S rDNA in European pikes (Esox sp.).BMC genomics · 2017Article
- Linking maternal and somatic 5S rRNA types with different sequence-specific non-LTR retrotransposons.RNA (New York, N.Y.) · 2017Article
- Comparative Cytogenetics between Two Important Songbird, Models: The Zebra Finch and the Canary.PloS one · 2017Article
- Evidence of birth-and-death evolution of 5S rRNA gene in Channa species (Teleostei, Perciformes).Genetica · 2016Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRibosomal 5S genes are well known for the critical role they play in ribosome folding and functionality. These genes are thought to evolve in a concerted fashion, with high rates of homogenization of gene copies. However, the majority of previous analyses regarding the evolutionary process of rDNA repeats were conducted in invertebrates and plants. Studies have also been conducted on vertebrates, but these analyses were usually restricted to the 18S, 5.8S and 28S rRNA genes. The recent identification of divergent 5S rRNA gene paralogs in the genomes of elasmobranches and teleost fishes indicate that the eukaryotic 5S rRNA gene family has a more complex genomic organization than previously thought. The availability of new sequence data from lower vertebrates such as teleosts and elasmobranches enables an enhanced evolutionary characterization of 5S rDNA among vertebrates.
resultsWe identified two variant classes of 5S rDNA sequences in the genomes of Potamotrygonidae stingrays, similar to the genomes of other vertebrates. One class of 5S rRNA genes was shared only by elasmobranches. A broad comparative survey among 100 vertebrate species suggests that the 5S rRNA gene variants in fishes originated from rounds of genome duplication. These variants were then maintained or eliminated by birth-and-death mechanisms, under intense purifying selection. Clustered multiple copies of 5S rDNA variants could have arisen due to unequal crossing over mechanisms. Simultaneously, the distinct genome clusters were independently homogenized, resulting in the maintenance of clusters of highly similar repeats through concerted evolution.
conclusionsWe believe that 5S rDNA molecular evolution in fish genomes is driven by a mixed mechanism that integrates birth-and-death and concerted evolution.
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