ArticleJournal of the American Chemical Society2011
Colorimetric bacteria sensing using a supramolecular enzyme-nanoparticle biosensor.
Article in Journal of the American Chemical Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 354 citations in OpenAlex.
- Morphology-Dependent Sensitivity of Chitosan-Based Sensing Materials for the Colorimetric Detection of β-Glucuronidase From Pathogenic E. coli.Macromolecular bioscience · 2026Article
- Adenosine triphosphate-triggered lipase colorimetric assay for portable detection of bacterial contamination.Mikrochimica acta · 2026Article
- An engineered M13 phage-rGO electrochemical biosensor for rapid detection of viral protein in complex matrices.Scientific reports · 2026Article
- Fluorescent Carbon Dots from Disposable Masks: Pathogen Sensing and UV-Blocking Film Integration.Journal of fluorescence · 2025Article
- Gold Nanoparticle-based Biosensors for Point-of-Care Diagnostics: A Review of Sensing Nanoparticle Applications and Future Prospects.Combinatorial chemistry & high throughput screening · 2025Review
- Biosynthesis of Iron Oxide Nanoparticles by MarineMolecules (Basel, Switzerland) · 2024Article
- Development of Optical Differential Sensing Based on Nanomaterials for Biological Analysis.Biosensors · 2024Review
- Genetically engineered bacteriophages as novel nanomaterials: applications beyond antimicrobial agents.Frontiers in bioengineering and biotechnology · 2024Review
- Gold Nanoparticle-Based Colorimetric Biosensing for Foodborne Pathogen Detection.Foods (Basel, Switzerland) · 2023Review
- Iron Oxide Nanoparticles: Green Synthesis and Their Antimicrobial Activity.Nanomaterials (Basel, Switzerland) · 2023Review
- Nano-Biotechnology for Bacteria Identification and Potent Anti-bacterial Properties: A Review of Current State of the Art.Nanomaterials (Basel, Switzerland) · 2023Review
- Metallic and Metal Oxides Nanoparticles for Sensing Food Pathogens-An Overview of Recent Findings and Future Prospects.Materials (Basel, Switzerland) · 2022Review
- Smartphone-based surface plasmon resonance sensing platform for rapid detection of bacteria.RSC advances · 2022Article
- Nanoceria-based lateral flow immunoassay for hydrogen peroxide-free colorimetric biosensing for C-reactive protein.Analytical and bioanalytical chemistry · 2022Article
- Rapid measurement of waterborne bacterial viability based on difunctional gold nanoprobe.RSC advances · 2022Article
- Spot tests: past and present.Chemtexts · 2022Article
- Nanotechnology for Targeted Detection and Removal of Bacteria: Opportunities and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- One-pot facile synthesis of enzyme-encapsulated Zn/Co-infinite coordination polymer nanospheres as a biocatalytic cascade platform for colorimetric monitoring of bacteria viability.Mikrochimica acta · 2021Article
- Rapid Fluorescence Quenching Detection ofSensors (Basel, Switzerland) · 2021Article
- Narrower Nanoribbon Biosensors Fabricated by Chemical Lift-off Lithography Show Higher Sensitivity.ACS nano · 2021Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Rapid and sensitive detection of pathogens is a key requirement for both environmental and clinical settings. We report here a colorimetric enzyme-nanoparticle conjugate system for detection of microbial contamination. In this approach, cationic gold nanoparticles (NPs) featuring quaternary amine headgroups are electrostatically bound to an enzyme [β-galactosidase (β-Gal)], inhibiting enzyme activity. Analyte bacteria bind to the NP, which releases the β-Gal and restores its activity, providing an enzyme-amplified colorimetric readout of the binding event. Using this strategy, we have been able to quantify bacteria at concentrations of 1 × 10(2) bacteria/mL in solution and 1 × 10(4) bacteria/mL in a field-friendly test strip format.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.