ArticleMedical physics2011
Comparison of 250 MHz electron spin echo and continuous wave oxygen EPR imaging methods for in vivo applications.
Article in Medical physics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 57 citations in OpenAlex.
- Accurate image reconstruction from reduced data in pulsed electron paramagnetic resonance imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2025Article
- Compact 1 GHz electron paramagnetic resonance spectrometer and imager.The Review of scientific instruments · 2025Article
- SOX71, A Biocompatible Succinyl Derivative of the Triarylmethyl Radical OX071 for In Vivo Quantitative Oxygen Mapping Using Electron Paramagnetic Resonance.Molecular imaging and biology · 2024Article
- Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024Article
- Directional TV algorithm for fast EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024Article
- Cyclic Disulfide-Bridged Dinitroxide Biradical for Measuring Thiol Redox Status by Electron Paramagnetic Resonance.The journal of physical chemistry. B · 2023Article
- 4D-image reconstruction directly from limited-angular-range data in continuous-wave electron paramagnetic resonance imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2023Article
- Biocompatible Monophosphonated Trityl Spin Probe, HOPE71, for In Vivo Measurement of pOAnalytical chemistry · 2023Article
- Rapid scan EPR: Automated digital resonator control for low-latency data acquisition.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022Article
- An iterative reconstruction algorithm without system matrix for EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022Article
- The Role of Imaging Biomarkers to Guide Pharmacological Interventions Targeting Tumor Hypoxia.Frontiers in pharmacology · 2022Review
- Evaluation of a Refined Implantable Resonator for Deep-Tissue EPR Oximetry in the Clinic.Applied magnetic resonance · 2021Article
- Multimodal Functional Imaging for Cancer/Tumor Microenvironments Based on MRI, EPRI, and PET.Molecules (Basel, Switzerland) · 2021Review
- Going Low in a World Going High: The Physiologic Use of Lower Frequency Electron Paramagnetic Resonance.Applied magnetic resonance · 2020Article
- Article
- EPR-based oximetric imaging: a combination of single point-based spatial encoding and TMagnetic resonance in medicine · 2018Article
- Optimization-based image reconstruction from sparsely sampled data in electron paramagnetic resonance imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2018Article
- Resonators for In Vivo Imaging: Practical Experience.Applied magnetic resonance · 2017Article
- In vivo preclinical cancer and tissue engineering applications of absolute oxygen imaging using pulse EPR.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017Review
- Feasibility of in vivo three-dimensional TMagma (New York, N.Y.) · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe authors compare two electron paramagnetic resonance imaging modalities at 250 MHz to determine advantages and disadvantages of those modalities for in vivo oxygen imaging.
methodsElectron spin echo (ESE) and continuous wave (CW) methodologies were used to obtain three-dimensional images of a narrow linewidth, water soluble, nontoxic oxygen-sensitive trityl molecule OX063 in vitro and in vivo. The authors also examined sequential images obtained from the same animal injected intravenously with trityl spin probe to determine temporal stability of methodologies.
resultsA study of phantoms with different oxygen concentrations revealed a threefold advantage of the ESE methodology in terms of reduced imaging time and more precise oxygen resolution for samples with less than 70 torr oxygen partial pressure. Above 100 torr, CW performed better. The images produced by both methodologies showed pO2 distributions with similar mean values. However, ESE images demonstrated superior performance in low pO2 regions while missing voxels in high pO2 regions.
conclusionsESE and CW have different areas of applicability. ESE is superior for hypoxia studies in tumors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.