Evidence map›Paper›PMID 21626524›Full record

ReviewHepatology (Baltimore, Md.)2011

CXC chemokine signaling in the liver: impact on repair and regeneration.

Heather L Van Sweringen, Nozomu Sakai, Amit D Tevar, Justin M Burns, Michael J Edwards, Alex B Lentsch

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Hepatology (Baltimore, Md.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Frontiers in immunology · 2024
    Article
  5. Article
  6. Article
  7. The immunological function of CXCR2 in the liver during sepsis.Journal of inflammation (London, England) · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Chemokine C-C motif ligand 33 is a key regulator of teleost fish barbel development.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  19. Review
  20. The Influence of Liver Resection on Intrahepatic Tumor Growth.Journal of visualized experiments : JoVE · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heather L Van SweringenDepartment of Surgery, University of Cincinnati, Cincinnati, OH 45267, USA.
Nozomu Sakai
Amit D Tevar
Justin M Burns
Michael J Edwards
Alex B Lentsch
University of Cincinnati · US

Funding

REGULATION OF HEPATIC ISCHEMIA/REPERFUSION INJURYR01DK056029 · NIDDK · UNIVERSITY OF LOUISVILLE · PI LENTSCH, ALEX B. · 2000 to 2018
$6.0M
Age Effects on Liver Inflammation and InjuryR01AG025881 · NIA · UNIVERSITY OF CINCINNATI · PI LENTSCH, ALEX B. · 2005 to 2014
$3.0M
NIA NIH HHS AG025881NIA NIH HHS R01 AG025881NIDDK NIH HHS DK56029NIDDK NIH HHS R01 DK056029
6 · The paper itself

Abstract

The process of liver repair and regeneration following hepatic injury is complex and relies on a temporally coordinated integration of several key signaling pathways. Pathways activated by members of the CXC family of chemokines play important roles in the mechanisms of liver repair and regeneration through their effects on hepatocytes. However, little is known about the signaling pathways used by CXC chemokine receptors in hepatocytes. Here we review our current understanding of the pathways involved in both CXC chemokine receptor signaling in other cell types, most notably neutrophils, and similar pathways operant during hepatocyte proliferation/liver regeneration to formulate a basis for the function of CXC chemokine receptor signaling in hepatocytes.

Indexed as

Signal TransductionAnimalsChemokine CXCL2Chemokines, CXCHepatocytesHumansLiver DiseasesLiver RegenerationReceptors, ChemokineSensitivity and SpecificityChemokine CXCL2Chemokines, CXCReceptors, Chemokine

Identifiers

PMID21626524
PMCPMC3175305
OpenAlexW2043272995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.