Evidence map›Paper›PMID 21626326›Full record

ArticleSurgery today2011

Trends in the treatment outcomes for advanced colorectal cancer: an analysis at a single community hospital in Japan.

Morimasa Tomikawa, Daisuke Korenaga, Tomohiko Akahoshi, Kenichi Kohshi, Keishi Sugimachi, Yasuharu Ikeda, Kenji Takenaka, Yoshihiko Maehara

Abstract read
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Article in Surgery today, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Morimasa TomikawaDepartment of Surgery, Fukuoka City Hospital, Fukuoka, 812-0046, Japan.
Daisuke Korenaga
Tomohiko Akahoshi
Kenichi Kohshi
Keishi Sugimachi
Yasuharu Ikeda
Kenji Takenaka
Yoshihiko Maehara

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the trends in the treatment outcomes for patients with colorectal cancer in Japan.

methodsWe performed a retrospective analysis of patients undergoing surgery for primary colorectal cancer during a 16-year period (Group A [1992-2000, n = 258]; Group B [2001-2008, n = 258]) at Fukuoka City Hospital. Because no significant differences were found in the survival rates in stage 0, I, II, and III patients between the two groups, we concentrated on examining stage IV patients.

resultsThe 3-year survival rate for stage IV patients in Group B (n = 26) was significantly higher than that in Group A (n = 31) (34.9% vs 3.9%, P < 0.05). The rate of curative resection for advanced liver metastases in Group B patients was also significantly higher than that of Group A patients (50.0% vs 13.3%, P < 0.05). As a result, the 2-year survival rate for the disease-free patients in Group B was significantly higher than that for the non-disease-free patients in Group B (46.0% vs 21.0%, P < 0.05). Group B had a greater proportion of patients receiving l-leucovorin/5-fluorouracil than Group A (8 patients vs none, P < 0.05).

conclusionsRecent advances in surgical innovations and the utilization of new chemotherapeutic agents may have led to significant improvements in the treatment outcomes for advanced colorectal cancer in Japan.

Indexed as

AgedColorectal NeoplasmsFemaleHospitals, CommunityHumansJapanMaleMiddle AgedNeoplasm StagingRetrospective StudiesSurvival AnalysisTreatment Outcome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.